孙忠实，朱明炜(1.解放军海军总医院，北京　100048； .北京医院普外科，北京　100730)



·热点关注·

新型糖电解质输液在外科液体治疗的应用

孙忠实1 *，朱明炜2(1.解放军海军总医院，北京100048； 2.北京医院普外科，北京100730)

DOI10.14009/j.issn.1672-2124.2016.02.001

摘要液体治疗的进步是伴随着对人体体液代谢病理生理机制认识的深入、输液产品的开发和临床监测手段的完善而发展的。体液容量、渗透压及电解质含量是维持机体正常代谢、内环境稳定和各器官功能的基本保证。外科患者由于疾病、禁食、手术创伤等原因导致体液平衡失调而需要进行合理的液体治疗。为此，合理选择液体的种类、剂量，有效地维持体/微循环的稳定，保证组织器官功能的正常运转，降低围术期并发症的发生率，对改善患者的预后极为重要。目前，常用的液体治疗药物主要有晶体液和胶体液两大类。近年来，晶体液中以混合糖电解质为代表的新型糖电解质输液得到了快速发展，是临床补液治疗的基础药物之一。本文就外科液体治疗的目的、相关理论、具体方案和新型糖电解质输液的临床应用进行综述。

关键词新型糖电解质输液； 外科液体治疗； 混合糖电解质

Application of New Glucose and Electrolyte Infusion in Surgical Liquid Treatment

SUN Zhongshi1, ZHU Mingwei2(1.Navy General Hospital, Beijing 100048, China; 2.Dept.of General Surgery, Beijing Hospital, Beijing 100730, China)

ABSTRACTOBJECTIVE：The progress of liquid treatment is developing with the accompany of the deep understanding of the body fluid metabolism pathological physiological mechanism, research of infusion products and improvement of the clinical monitoring means. Fluid capacity, osmotic pressure and electrolyte content are the basic guarantee for maintaining matter metabolism, stable internal environment and physiological function in human body. The surgical patients were suppose to get rational fluid therapy for the disorder of body fluid balance caused by disease, fasting and surgical trauma, etc. Therefore, it is important to improve the prognosis of patients by the rational selection of types and dosage, the effective maintaining of systemic circulation and microcirculation, the normal operation of organ function and the reduction of incidence of perioperative complications. At present, the commonly used liquid are liquid crystal and colloid. Carbohydrate and electrolyte injection as one of the basic drugs for liquid treatment in clinic, on behalf of crystal infusion of new glucose electrolyte solution, developed rapidly in recent years. This thesis aims to review the purpose, the related theories, concrete proposal of surgical liquid treatment and the clinical application of new glucose and electrolyte infusion.

KEYWORDSNew glucose and electrolyte infusion; Surgical liquid treatment; Carbohydrate and electrolyte injection

1外科液体治疗的目的

临床上多种因素容易导致外科患者低血容量，诸如禁食、不感蒸发增加、失血、第三间隙效应等。充分而恰当的液体治疗，能够有效防止低血容量的发生，从而确保足够的心输出量和氧输送量。因此，液体治疗在患者整个住院治疗的过程中有着举足轻重的作用[1]。……