向荣梅(汉川市人民医院小儿内科，湖北 汉川　431600)



盐酸氨溴索注射液雾化吸入治疗小儿支气管肺炎的疗效观察

向荣梅*(汉川市人民医院小儿内科，湖北 汉川431600)

DOI10.14009/j.issn.1672-2124.2016.02.014

摘要目的：探讨盐酸氨溴索注射液雾化吸入治疗小儿支气管肺炎的临床效果。方法：选取汉川市人民医院2013年7月—2014年7月收治的100例小儿支气管肺炎患者作为研究对象，通过双色球随机分组法分为观察组和对照组各50例。对照组患儿采用常规治疗，观察组患儿在此基础上加以盐酸氨溴索注射液雾化吸入辅助治疗，观察2组患儿的治疗效果及不良反应发生情况。结果：观察组患儿治疗有效率为96.00%(48/50)，高于对照组的86.00%(43/50)，差异有统计学意义(P<0.05)；观察组患儿咳嗽消失时间为(4.20±1.20) d，气促消失时间为(3.40±1.10) d，啰音消失时间为(4.10±1.80) d，住院时间时间为(5.90±1.50) d，均明显短于对照组的(6.50±1.70)、(5.60±1.80)、(6.50±1.20)、(7.60±1.00) d，差异均有统计学意义(P<0.05)；2组患儿不良反应发生率比较，差异无统计学意义(P>0.05)。结论：小儿支气管肺炎患者在常规治疗基础上给予盐酸氨溴索注射液雾化吸入治疗，可明显改善临床症状，不良反应少，疗效显著，值得临床推广。

关键词小儿支气管肺炎； 盐酸氨溴索注射液雾化吸入； 临床效果

Observation on Efficacy of Ambroxol Hydrochloride Injection Inhalation in Treatment of Children with Bronchial Pneumonia

XIANG Rongmei(Dept.of Pediatric Internal Medicine，People’s Hospital of Hanchuan, Hubei Hanchuan 431600, China)

ABSTRACTOBJECTIVE：To investigate the clinical effects of ambroxol hydrochloride injection inhalation in treatment of children with bronchial pneumonia. METHODS: 100 cases of children with bronchial pneumonia admitted into People’s Hospital of Hanchuan from Jul. 2013 to Jul. 2014 were selected to be divided into observation group and control group via he double chromosphere random grouping method, with 50 cases in each. The control group received conventional therapy, while the observation group were additionally treated with ambroxol hydrochloride injection inhalation as adjuvant therapy based on the control group; the treatment effects and adverse reactions in two group of patients were observed. RESULTS: The effective rate in observation group was 96.00%(48/50), higher than that in the control group 86.00%(43/50), with statistically significant difference (P<0.05). In observation group, disappearance time of cough was (4.20±1.20) d, disappearance time of anhelation was (3.40±1.10) d, disappearance time of rale was (4.10±1.80) d and length of stay was (5.90±1.50) d, significantly shorter than that in control group (6.50±1.70) d,(5.60±1.80) d,(6.50±1.20) d and (7.60±1.00) d, with statistically significant difference(P<0.05). There was no significant difference in the incidence of adverse reactions between two group of patients(P>0.05).CONCLUSIONS: For children with bronchial pneumonia, the treatment of ambroxol hydrochloride injection inhalationon based on the conventional treatment can significantly improve the clinical symptoms, with few adverse reactions and significant efficacy; it is worthy of clinical promotion.

KEYWORDS Bronchial pneumonia in children; Ambroxol hydrochloride injection inhalation; Clinical effects

小儿支气管肺炎是儿科临床常见病和多发病，多因细菌、病毒感染所致。由于小儿气管、支气管狭窄，黏膜细胞分泌少，肺泡细胞发育不成熟，病原菌清除能力低下，为细菌、病毒的滋生繁殖提供了有利条件[1-2]。临床治疗小儿支气管肺炎，除积极控制感染、保持呼吸道通畅、纠正缺氧、退热、利尿剂、抗心力衰竭、防治并发症外，还可应用盐酸氨溴索注射液雾化吸入治疗。本研究探讨盐酸氨溴索注射液雾化吸入治疗小儿支气管肺炎效果，现报告如下。

1资料与……