亚低温治疗急性重度颅脑损伤40例临床观察

何雄飞

四川省成都市新都区人民医院神经外科，四川成都610500

【摘要】目的：观察对急性重度颅脑损伤患者采用亚低温治疗的临床疗效。方法：选取急性重度颅脑损伤患者80例作为临床研究对象，使用随机数字表法将其随机分为研究组和对照组，每组各40例。对照组患者给予常规的颅脑损伤治疗方式；研究组患者在对照组的治疗基础上给予亚低温进行治疗。观察和比较两组患者的临床疗效。结果：两组患者治疗后的GCS评分均明显高于治疗前，其中又以研究组的差异更为明显，差异均有统计学意义(P<0.05)。研究组治疗后的恢复良好率明显高于对照组，死亡率明显低于对照组，差异均有统计学意义(P<0.05)。结论：对急性重度颅脑损伤患者采用亚低温治疗具有良好的临床疗效，有助于改善患者的预后，值得在临床上进一步推广。

【关键词】亚低温；急性重度颅脑损伤；临床观察

作者简介：何雄飞,男,本科,主治医师。

【中图分类号】R651.1`+5

【文献标志码】A

【文章编号】1007-8517(2015)21-0045-02

Abstract:Objective To study on acute severe craniocerebral injury patients with clinical curative effect of mild hypothermia therapy.Methods 80 patients were randomly divided into study group and control group, 40 cases in each group. Compared to the conventional treatment of traumatic brain injury treated with mild hypothermia group, the treatment group in the control group of patients. Observe and compare clinical effects of two groups of patients. Results the study group after treatment, the GCS score was significantly higher than that of the control group(P<0.05), the differences were statistically significant. The good recovery rate of the study group after treatment was significantly higher than the control group, mortality was significantly lower than that of the control group(P<0.05), the differences were statistically significant. Conclusion The patients with acute severe brain injury with mild hypothermia therapy has a good clinical effect, can improve the prognosis of the patients, it is worthy of further promotion in clinical.

Keywords:Acute hypothermia; severe brain injury; clinical efficacy; prognosis

收稿日期：(2015.07.29)

Clinical observation of 40 cases of mild hypothermia in treatment of acute severe brain injury

HE Xiongfei

Department of Neurosurgery,People's Hospital of Xindu District of Chengdu City,Chengdu,610500,China

急性重度颅脑损伤的致残率和死亡率都比较高，严重威胁了患者的身体健康和生命安全[1]。因此，如何提高急性重度颅脑损伤患者的治疗效果始终是临床上重点关注的问题。本次研究选取我院收治的急性重度颅脑损伤患者80例作为临床研究对象，现将结果报告如下。

1资料与方法

1.1一般资料本次研究选取我院2013年1月至2015年1月间收治的急性重度颅脑损伤患者80例作为临床研究对象，纳入标准[2]：①发病至就诊时间低于1d；②患者的格拉斯哥昏迷评分(GCS)≤8分；③受伤原因属于颅内损伤，且排除由于心脑血管疾病引发的脑出血和脑梗死疾病；④患者及家属均同意参与本次研究，且签署《知情同意书》。……