15%恶霉灵悬浮种衣剂配方筛选研究
2015-10-21王睿汤智鹏李茜陈朝东高成康杨春平
王睿 汤智鹏 李茜 陈朝东 高成康 杨春平


摘要
[目的]探讨15%恶霉灵悬浮种衣剂的研制配方,为恶霉灵的推广和应用提供参考。[方法]采用湿式超微粉碎法制备了15%恶霉灵悬浮种衣剂,并通过对成膜剂、增稠剂、乳化剂、分散剂、防冻剂进行筛选确定了优化配方。[结果]15%恶霉灵悬浮种衣剂的优化配方为:15.0%恶霉灵、3.0% PVA、5.0% 602#、3.0%木钙、0.2%黄原胶、4.0%乙二醇、0.5%玫瑰精、余量为水。经低温[(0±2)℃,7 d]和热贮[(54±2)℃,14 d]稳定性试验,制剂外观无明显分层,水中分散性良好,各项指标均符合悬浮种衣剂相关标准。[结论]为恶霉灵悬浮种衣剂的开发奠定了基础。
关键词 恶霉灵;悬浮种衣剂;配方筛选
中图分类号 S482.2 文献标识码 A 文章编号 0517-6611(2015)03-120-03
Formulation Preparation of 15% Hymexazol Seedcoating
WANG Rui1, TANG Zhipeng2, LI Qian1, YANG Chunping5* et al
(1. Qingbaijiang Rural Development Bureau of Chengdu City, Qingbaijiang, Sichuan 610300; 2. Sichuan EntryExit Inspection and Quarantine Bureau, Chengdu, Sichuan 610000; 5. College of Agriculture, Sichuan Agricultural University, Chengdu, Sichuan 611130)
Abstract [Objective] The formulation preparation of 15% Hymexazol seedcoating was explored to provide reference for application and population of the agent. [Method] The experiment in the screening of such effective adjuvant as film forming agent, thickening agent, emulsifying agent, dispersing agent and anti freezing agent was conducted according to different indicators with the method of wet milling. Based on the indicators, optimum was obtained. [Result] After primary screening, the best determined formula was as follows: Hymexazol 15.0%, PVA 3.0%, 602# 5.0%, wooden calcium 3.0%, xanthan gum 0.2%, ethylene glycol 4.0%, rose essence 0.5%,with additional water up to 100%. The results indicated that under the condition of (0 ± 2) ℃ for 7 d and (54 ± 2) ℃ for 14 d, the character of formed membrane was perfect which was in accordance with the experimentally relevant determined standards. [Conclusion] The results lay the basis for the development of 15% Hymexazol seedcoating.
Key words Hymexazol; Seedcoating agent; Formulation screening
基金項目 公益性行业(农业)科研专项(nyhyzx315);四川省科技厅应用基础项目(2012JY0117)。
作者简介
王睿(1980-),女,内蒙古包头人,硕士,从事植物保护及生物研究。*通讯作者,副教授,博士,从事天然产物农药研发及生物防治研究。
收稿日期 20141209
悬浮型种衣剂是当今使用最广泛,应用最安全、环保,且最经济有效的种子处理剂类型,它是一种含有成膜剂、以水为介质直接或稀释后用于种子包衣的稳定悬浮液种子处理剂[1],其特点是在土壤中遇水膨胀,透气而不被溶解,从而使种子正常发芽,使农药化肥缓慢释放,能有效杀灭地下害虫,防治种子病菌,提高种子发芽率,减少种子使用量[2-8]。
恶霉灵是一种高效广谱杀菌剂,对土传真菌如腐霉菌、镰刀菌、丝核菌等病原引起的病害都有良好的防治效果[9-11]。按照绿色食品的生产要求应加大恶霉灵的推广,限制和淘汰高毒、中毒杀菌剂的生产和使用,从根本上减轻农药对土壤和农产品的污染,使生态农业的战略目标早日实现[9]。……
