全胸腔镜肺叶切除术治疗早期肺癌合并慢性阻塞性肺疾病患者的临床研究
2015-10-21王涛等
王涛等


【摘要】 目的 探讨全胸腔镜肺叶切除术治疗早期肺癌合并慢性阻塞性肺疾病患者的临床效果。 方法 将48例早期非小细胞肺癌合并慢性阻塞性肺疾病患者分为全胸腔镜组(研究组)22例,单纯小切口组(对照组)26例,比较2组患者围手术期的临床指标。结果 研究组术中出血量、术后24小时引流量、术后1d疼痛评分、术后住院天数等指标均显著低于对照组(P ﹤0.05)。两组手术时间、淋巴结清扫数目枚、术后并发症发生率比较差异无显著性(P > 0.05)。结论 全胸腔镜肺叶切除术治疗早期肺癌合并慢性阻塞性肺疾病较单纯小切口手术创伤更小,术后恢复快。
【关键词】胸腔镜;非小细胞肺癌;肺叶切除术;慢性阻塞性肺疾病;
【Abstract】 Objective To evaluate the clinical outcome of complete video-assisted thoracoscopic surgery(VATS) lobectomy for patients with early-stage non-small cell lung cancer and chronic obstructive pulmonary disease (COPD). Methods We analyzed the clinical data of 48 patients with early-stage NSCLC and COPD, all patients were randomly divided into the the VATS group (observation group, 22 cases) or the routine small incision open-chest lobectomy group (control group, 26 cases). Perioperative clinical parameters of 2 groups were compared. Results All data showed that intraoperative blood loss in patients, post-operative drainage in 24 hours, VAS score, post operation hospitalization duration of the observation group were significantly less than the control group(P<0.05). The operative time, the mean group of lymph node dissection, incidence of postoperative complications showed there were no statistically significant difference between the two groups(P>0.05). Conclusion Complete video-assisted thoracoscopic surgery lobectomy for patients with early-stage NSCLC and COPD offers less injury and a more rapid recovery than routine small incision open-chest lobectomy.
【key words 】Video-assisted thoracoscopic surgery, Non-small cell lung cancer, pneumonectomy, Chronic obstructive pulmonary disease
【中图分类号】R722.12 【文献标识码】B【文章编号】1004-4949(2015)02-0001-01
慢性阻塞性肺疾病(Chronic obstructive pulmonary disease,COPD简称慢阻肺)合并肺癌在临床上较为多见,吸烟是肺癌和慢性阻塞性肺疾病主要病因,研究表明慢性阻塞性肺疾病是肺癌的一个重要的独立危险因素 。慢阻肺患者肺功能明显降低,肺癌的外科手术治疗常受到一定的限制。寻找一种肺癌合并慢阻肺患者能够耐受,手术效果令人满意,与传统开胸手术比较并发症及创伤性更小、更安全的手术方式就成为本次研究的目的。
电视胸腔镜手术(Video-assisted thoracoscopic surgery, VATS)是20世纪90年代迅速发展起来的一种全新的胸外科手术技术。胸腔镜手术被越来越多的胸外科医师及患者所接受2-4。随着手术技术的不断提高以及手术器械的不断改进,胸腔镜手术适应症也越来越广泛。探……
