利巴韦林联合炎琥宁治疗小儿疱疹性咽峡炎的效果观察
2015-03-24陈练等
陈练等
[摘要] 目的 探讨利巴韦林联合炎琥宁治疗小儿疱疹性咽峡炎的临床效果。 方法 选取2011年1月~2014年10月于本院诊治的疱疹性咽峡炎患儿104例,将其随机分为治疗组(56例)和对照组(48例),治疗组在常规综合治疗的基础上给予利巴韦林联合炎琥宁治疗,对照组在常规综合治疗的基础上单用炎琥宁治疗。比较两组的临床疗效。 结果 治疗组总有效率为98.2%,高于对照组的72.9%,差异有统计学意义(P<0.05)。 结论 利巴韦林联合炎琥宁治疗疱疹性咽峡炎效果显著,不良反应少,值得临床推广。
[关键词] 疱疹性咽峡炎;利巴韦林;炎琥宁;小儿
[中图分类号] R725.6 [文献标识码] A [文章编号] 1674-4721(2015)02(b)-0120-02
Efficacy observation of ribavirin combined with Yanhuning in treatment of infantile herpangina
CHEN Lian HUA Xiao-xing MAI Hua-zhuo
Department of Pediatrics,Maoming People′s Hospital of Guangdong Province,Maoming 525000,China
[Abstract] Objective To investigate the clinical effect of ribavirin combined with Yanhuning in treatment of infantile herpangina. Methods 104 cases of children diagnosed as herpangina in our hospital from January 2011 to October 2014 were seleced,and were randomly divided into treatment group (56 cases) and control group (48 cases).Treatment group were given with ribavirin combined with Yanhuning on the basis of routine treatment,control group were taken with Yanhuning simply on the basis of routine treatment.The efficacy of the two groups was compared. Results The total effective rate of treatment group was 98.2%,higher than 72.9% of control group,the difference was significant (P<0.05). Conclusion Ribavirin combined with Yanhuning has significant effect in treatment of herpangina,with less adverse reaction,it is worthy of clinical popularization and application.
[Key words] Herpangina;Ribavirin;Yanhuning;Infantile
疱疹性咽峡炎为儿科常见病、多发病[1-3],是小儿急性上呼吸感染中的一种特殊类型,该疾病多由A组柯萨奇病毒感染引起,呼吸道合胞病毒、流感病毒等亦可导致发病[4]。对疱疹性咽峡炎患儿如若不及时进行治疗,则可能因为其易反复发作的特点而引起慢性肾炎等。探讨利巴韦林联合炎琥宁治疗小儿疱疹性咽峡炎的临床效果。
1 资料与方法
1.1 一般资料
选取2011年1月~2014年10月于本院诊治的疱疹性咽峡炎患儿104例,均符合《儿科学》[5]中疱疹性咽峡炎的诊断标准,均有发热,体温为38.3~40.2℃。将104例患儿随机分为治疗组(56例)和对照组(48例),治疗组中,男32例,女24例;年龄6个月~5岁,平均(3.1±0.8)岁。对照组中,男27例,女21例;年龄8个月~6岁,平均(3.2±0.9)岁。两组患儿的一般资料比较,差异无统计学意义(P>0.05),具有可比性。
1.2 治疗方法
两组患儿均给予常规治疗,包括镇咳祛痰、补液及维生素营养支持等,治疗组在此基础上给予注射用利巴韦林(海南通用康力制……
