刘文姬+梁群兴+刘宏锋

[摘要] 目的 观察曲马多联合氟哌利多治疗无痛人工流产中米索前列醇宫颈上药引起寒战的效果。 方法 对26例超声引导下无痛人工流产孕妇因使用米索前列醇宫颈上药引起寒战应用曲马多合并氟哌利多治疗的效果进行观察分析。 结果 优25例（96.2%）；良1例（3.8%）；差0例（0）。 结论 曲马多联合氟哌利多治疗人工流产中米索前列醇宫颈上药引起寒战的效果显著，减轻了患者手术的痛苦，极大提高了人工流产的安全性与质量，值得在临床推广和应用。

[关键词] 米索前列醇；曲马多；氟哌利多；人工流产；寒战

[中图分类号] R714.21[文献标识码] A[文章编号] 1674-4721（2014）03（c）-0083-02

Efficacy observation of tramadol combining with droperidol in the treatment of shivering caused by applying misoprostol to uterine neck in painless induced abortion

LIU Wen-ji1 LIANG Qun-xing1 LIU Hong-feng2

1.Shiqiao Hospital of Panyu District in Guangzhou City,Guangzhou 511400,China;2.Shawan People′s Hospital of Panyu District in Guangzhou City,Guangzhou 511483,China

[Abstract] Objective To observe the efficacy of tramadol combining with droperidol in the treatment of shivering caused by applying misoprostol to uterine neck in painless induced abortion.Methods The efficacy of usingtramadolanddroperidol on treating shivering caused by applying misoprostol to uterine neck in painless induced abortion was observed and analyzed in 26 pregnant women under the ultrasonic guidance. Results The therapeutic effect was excellent in 25 cases (96.2%),and good in one case (3.8%). Conclusion Combination of tramadol and droperidol can obtain remarkable effect in the treatment of shivering caused by applying misoprostol to uterine neck in induced abortion,alleviate patient′s suffering by surgery,and greatly improve the safety and quality of induced abortion,which is worthy of expansion in clinic.

[Key words] Misoprostol;Tramadol;Droperidol;Induced abortion;Shivering

人工流产术为有创伤性手术，术前宫颈扩张是最关键的步骤，机械性宫颈扩张容易损伤宫颈，诱发人工流产综合征，国内外对人工流产术前应用药物进行宫颈扩张进行了大量研究，米索前列醇是前列腺素的衍生物，近年来，发现其同体内分泌的前列腺素一样能使子宫收缩[1]，软化和扩张宫颈，减轻疼痛，减小宫颈损伤，效果良好，临床上应用较广，得到广大患者的认可和接受；在实际工作中，使用米索前列醇宫颈上药虽然可减轻人工流产的痛苦，但也存在较大弊端，如可引起患者在麻醉前、手术中、苏醒后较剧烈的寒战，曲马多联合氟哌利多治疗米索前列醇宫颈上药引起寒战的效果显著，现报道如下。

1 资料与方法

1.1 一般资料

选取2013年9月～2014年2月超声引导下无痛人工流产中26例使用米索前列醇宫颈上药引起寒战的孕妇为观察对象，年龄为18～40岁，孕5～9周，体重45～70 kg，ASAⅠ～Ⅱ级；……