王玉卿，尤国美，余先萍，俞炎平，姚 征

(浙江省肿瘤医院，浙江 杭州 310022)

·基础与临床研究·

CT导向下I125放射性粒子植入治疗晚期胰腺癌的护理

王玉卿，尤国美，余先萍，俞炎平，姚 征

(浙江省肿瘤医院，浙江 杭州 310022)

目的： 探讨CT导向下I125放射性粒子植入治疗晚期胰腺癌的护理。方法对21例CT导向下I125放射性粒子植入治疗晚期胰腺癌的患者给予周到细致的护理，包括心理护理，术前护理，术中配合，术后并发症的防治，放射防护护理，健康教育等护理措施。结果全部患者顺利完成粒子植入治疗。其中3例患者术后有轻度胰腺炎症状，6例患者术后中度疼痛，15例患者术后轻度疼痛，10例患者体温达到38.6～39.1℃。21例患者均未发生出血及肺栓塞并发症。结论全面、周到、细致的护理是顺利完成CT导向下I125放射性粒子植入治疗晚期胰腺癌的重要保证。

I125放射性粒子；植入治疗；晚期胰腺癌；护理

Abstract: [Objective] To investigate the clinic nursing of CT-guided ioding-125 seed implantation therapy in patients with advanced pancreatic cancer. [Method] 21 patients with advanced pancreatic cancer who were treated by CT- guided ioding-125 seed implantation therapy were enrolled in this study. These patients received clinic nursing that included psychologic nursing, preoperative care, intraoperative cooperate and so on. [Result] After treatment , 3 patients occurred mild pancreatitis, 6 patients experienced severe pain and ten patients’ temperature reached 38.6 ～ 39℃. [Conclusion] A comprehensive, thoughtful and careful nursing is the great standing policy of successfully complete ct-guided ioding-125 seed implantation therapy in patients with advanced pancreatic cancer。

Keywords:Ioding-125 Seed：implant treatment：advanced pancreatic cancer：clinic nursing

I125粒子植入属于近距放射治疗的一种，通过持续发出的低能量(27～35keV)γ射线，毁灭杀伤肿瘤而不损伤正常组织[1]，临床应用证实对前列腺癌、胰腺癌、肝癌、乳腺癌、肺癌等疗效肯定，表现为肿瘤组织缩小、转移和复发减少、生存率提高。同时由于放射源周围剂量分布是按照与放射源距离的平方反比的方式下降，邻近的周围组织，如肠道、肠系膜动、静脉等受到的影响较小，减少了并发症的发生率[2]。我院介入科于2010年6月至 2011年8月对21例失去手术治疗机会的晚期胰腺癌患者进行CT导向下I125放射性粒子植入治疗，现将护理体会报告如下。……