黄燕珠

【摘要】 目的：探究新生儿早期基本保健对新生儿生化指标及生理状态的影响。方法：将2022年6月—2023年5月晋江市医院的100例新生儿根据随机数字表法分为对照组50例和观察组50例。对照组进行常规干预，观察组则进行新生儿早期基本保健。比较两组干预前后的生长发育指标（体重及上臂围）、生化指标[肝肾功能指标（血肌酐、尿素氮及胆红素）及免疫指标免疫黏附促进因子（FEER）、免疫黏附抑制因子（FEIR）、CD3+及免疫球蛋白G（IgG）]及生理状态指标（血氧饱和度、心率、呼吸频率及体温）。结果：干预前两组的生长发育指标、生化指标及生理状态指标比较，差异均无统计学意义（P>0.05），干预后2周及4周观察组的生长发育指标、FEER、CD3+、IgG、血氧饱和度及体温均显著高于对照组，肝肾功能指标、FEIR、心率及呼吸频率均显著低于对照组，差异均有统计学意义（P<0.05）。结论：新生儿早期基本保健可显著改善新生儿生化指标及生理状态，因此在新生儿中的应用价值相对较高。

【关键词】 新生儿 早期基本保健 生化指标 生理状态

Influence of Early Basic Healthcare of Newborns on Biochemical Indexes and Physiological State of Newborns/HUANG Yanzhu. //Medical Innovation of China， 2024， 21（14）： 0-073

[Abstract] Objective： To investigate the influence of early basic healthcare of newborns on biochemical indexes and physiological state of newborns. Method： A total of 100 newborns in Jinjiang Hospital from June 2022 to May 2023 were divided into control group 50 cases and observation group 50 cases by the random number table. The control group was treated with routine intervention， the observation group was treated with early basic healthcare of newborns. Then the growth and development indexes （body weight and upper arm circumference）， biochemical indexes [liver and kidney function indexes （blood creatinine， urea nitrogen and bilirubin） and immune indexes immune adhesion promoting factor （FEER）， immunoadhesive inhibitory factor （FEIR）， CD3+ and immunoglobulin G （IgG）] and physiological state indexes （blood oxygen saturation， heart rate， respiratory rate and body temperature）of two groups before and after the intervention were compared. Result： The growth and development indexes， biochemical indexes and physiological state indexes of two groups before the intervention were compared， the differences were not statistically significant （P>0.05）， the growth and development indexes， FEER， CD3+， IgG， blood oxygen saturation and body temperature of observation group at second and forth week after the intervention were significantly higher than those of control group， the liver and kidney function indexes， FEIR， heart rate and respiratory rate were significantly lower than those of control group， the differences were statistically significant （P<0.05）. Conclusion： The early basic healthcare of newborns can significantly improve the biochemical indexes and physiological state of newborns， so its application value in the newborns is relatively higher.

[Key words] Newborns Arly basic healthcare Biochemical indexes Physiological state

First-author's address： Department of Obstetrics， Jinjiang Hospital， Jinjiang 362200， China

doi：10.3969/j.issn.1674-4985.2024.14.017

新生儿的基本保健与其生长发育、健康状态等多方面密切相关，因此临床受肯定程度较高。临床中与新生儿相关的保健研究显示，正确有效的干预措施不仅有助于改善新生儿生理状态，且对其生化指标的表达也有较大的影响，因此对新生儿进行有效干预措施的制订与实施是临床重点[1-2]。临床中关于新生儿生化指标及生理状态干预的研究多见，其中关于新生儿早期基本保健在本类患儿中的应用研究可见，且多数研究认为其对于新生儿的干预效果较好[3-5]，但是其细致的作用研究不足，包括对新生儿生化指标及生理状态的影响研究更为匮乏。本研……