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ICU缺血性脑卒中患者下肢深静脉血栓形成危险因素分析

2024-05-21吴蕾

中国医学创新 2024年8期
关键词:危险因素

吴蕾

【摘要】 目的:分析重癥监护室(ICU)缺血性脑卒中患者下肢深静脉血栓形成(DVT)发生的危险因素。方法:回顾性分析2021年5月—2023年4月贵州医科大学附属医院收治的96例ICU缺血性脑卒中患者的临床资料,统计其DVT发生率;收集患者的年龄、性别等资料,分析患者DVT发生的危险因素。结果:96例ICU缺血性脑卒中患者中,共有28例发生DVT,占比29.17%。单因素分析显示:发生组的年龄>60岁、体重指数(BMI)>24 kg/m2、有高血压史、有糖尿病史、C反应蛋白(CRP)水平>10 mg/L、D-二聚体(D-D)水平>0.5 mg/L占比均高于未发生组,差异均有统计学意义(P<0.05);两组性别、吸烟史、饮酒史、高脂血症占比相比,差异均无统计学意义(P>0.05)。logistic回归分析显示:年龄>60岁[OR=7.459,95%CI(2.804,19.846)]、BMI>24 kg/m2[OR=2.833,95%CI(1.144,7.017)]、有高血压史[OR=3.796,95%CI(1.464,9.846)]、有糖尿病史[OR=5.160,95%CI(1.923,13.849)]、CRP>10 mg/L[OR=7.667,95%CI(2.721,21.601)]、D-D>0.5 mg/L[OR=2.908,95%CI(1.165,7.258)]是ICU缺血性脑卒中患者DVT发生的独立危险因素(P<0.05)。结论:ICU缺血性脑卒中患者DVT发生风险较高,其发生的危险因素包括年龄>60岁、BMI>24 kg/m2、有高血压史、有糖尿病史、CRP>10 mg/L、D-D>0.5 mg/L。

【关键词】 缺血性脑卒中 重症监护室 下肢深静脉血栓形成 危险因素

Analysis of Risk Factors for Lower Limb Deep Vein Thrombosis in ICU Ischemic Stroke Patients/WU Lei. //Medical Innovation of China, 2024, 21(08): -164

[Abstract] Objective: To analyze the risk factors for the development of lower limb deep venous thrombosis (DVT) in patients with ischemic stroke in intensive care unit (ICU). Method: A retrospective analysis was conducted on the clinical data of 96 ICU ischemic stroke patients admitted to the Affiliated Hospital of Guizhou Medical University from May 2021 to April 2023, and the incidence of DVT was calculated; the age, gender, and other data of patients were collected to analyze the risk factors of DVT. Result: Among the 96 ICU patients with ischemic stroke, 28 patients had DVT, accounting for 29.17%. Univariate analysis showed that age >60 years, body mass index (BMI) >24 kg/m2, history of hypertension, history of diabetes, C reactive protein (CRP) level >10 mg/L,

D-dimer (D-D) level >0.5 mg/L in the occurrence group were higher than those in the non occurrence group, the differences were statistically significant (P<0.05); there were no statistically significant differences in gender, smoking history, alcohol history, and proportion of hyperlipidemia in the two groups (P>0.05). logistic regression analysis showed that: age >60 years [OR=7.459, 95%CI (2.804, 19.846)], BMI >24 kg/m2 [OR=2.833, 95%CI (1.144, 7.017)], a history of hypertension [OR=3.796, 95%CI (1.464, 9.846)], a history of diabetes mellitus [OR=5.160, 95%CI (1.923, 13.849)], CRP >10 mg/L [OR=7.667, 95%CI (2.721, 21.601)], D-D >0.5 mg/L [OR=2.908, 95%CI (1.165, 7.258)] were independent risk factors for DVT in ischemic stroke patients in the ICU (P<0.05). Conclusion: The risk of DVT in patients with ischemic stroke in ICU is high. The risk factors of DVT include age >60 years old, BMI >24 kg/m2, history of hypertension, history of diabetes, CRP >10 mg/L, D-D >0.5 mg/L.

[Key words] Ischemic stroke Intensive care unit Deep venous thrombosis of lower limbs Risk factors

First-author's address: Department of Neurology, the Affiliated Hospital of Guizhou Medical University, Guiyang 550004, China

doi:10.3969/j.issn.1674-4985.2024.08.036

缺血性脑卒中为临床常见的脑血管疾病,具有起病急、进展快、致残致死率高等特征[1-2]。近年,因人口老龄化进程的加快,缺血性脑卒中的发生率逐年上涨,给广大居民的身心健康造成众多危害[3-4]。重症监护室(ICU)收治的缺血性脑卒中患者的病情危重,患者需长期卧床,故容易诱发较多并发症,其中以下肢深静脉血栓形成(DVT)较为常见。DVT一旦发生,将会延长患者住院时间,增加经济压力,还可能会加重原本病情,甚至危及生命[5]。因此,积极的了解ICU缺血性脑卒中患者DVT发生的影响因素意义重大。基于此,本研究回顾性分析2021年5月—2023年4月贵州医科大学附属医院收治的96例ICU缺血性脑卒中患者的临床资料,探究其DVT发生的危险因素,现报道如下。

1 资料与方法

1.1 一般资料

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