邓远中

[摘要]目的對慢性胃炎患者进行幽门螺杆菌根除性治疗联合益生菌治疗，对其治疗效果进行评价，并分析该治疗方法对胃泌素水平产生的影响。方法选择2015年1月至2021年3月兴宁市人民医院进行慢性胃炎治疗的患者40例作为本研究对象，对上述患者进行回顾性分析，依据不同治疗方式将其分成对照组与试验组，每组各20例，对照组患者采用常规幽门螺杆菌根除性治疗，试验组在对照组基础上增加益生菌治疗。比较两组患者的治疗效果、胃泌素水平以及幽门螺杆菌根除率。结果治疗后将两组患者的治疗总有效率进行比较，结果显示试验组优于对照组，分析两组患者的胃泌素水平，试验组改善效果优于对照组，比较两组患者幽门螺杆菌根除率，试验组比对照组根除率高（ P <0.05）。结论当患者被幽门螺杆菌感染后发生慢性胃炎，其体内胃泌素水平会出现异常，采用幽门螺杆菌根除性治疗联合益生菌治疗之后，患者胃泌素水平得到有效调整，呈现出下降状态，患者的症状逐渐得到缓解，生活质量得到提高，治疗效果比较显著。 [关键词]慢性胃炎;幽门螺杆菌根除性治疗;胃泌素水平;幽门螺杆菌根除率;益生菌

[中图分类号] R573.1  [文献标识码] A   [文章编号]2095-0616（2022）09-0173-04

Application effect of helicobacter pylori eradication therapy combined with probiotics in patients with chronic gastritis and its influence on gastrin levels

DENG  Yuanzhong

Department of Gastroenterology， Xingning People's Hospital， Guangdong， Xingning 514500， China

[Abstract] Objective To carry out helicobacter pylori eradication therapy combined with probiotics for patients with chronic gastritis， to evaluate the therapeutic effect， and to analyze the effect of the therapy on gastrin levels. Methods A total of 40 patients with chronic gastritis treated in Xingning People's Hospital from January 2015 to March 2021 were selected as the research objects. They were retrospectively analyzed and were divided into the control group and the experimental group according to different treatment methods， with 20 cases in each group. The control group received conventional helicobacter pylori eradication therapy， while the experimental group received probiotic therapy on the basis of the therapy of the control group. The therapeutic effect， gastrin level and helicobacter pylori eradication rate were compared between the two groups. Results After the treatment， the total effective rates of the two groups of patients were compared， and the results showed that the experimental group was better than the control group. The gastrin levels of the two groups of patients were analyzed， and the improvement effect of the experimental group was better than that of the control group. The helicobacter pylori eradication rate of the experimental group was higher than that of the control group （P <0.05）. Conclusion When chronic gastritis occurs in patients infected with helicobacter pylori combined with probiotics， the gastrin level in the body will be abnormal. After the eradication therapy of helicobacter pylori， the gastrin level of the patients will be effectively adjusted， showing a state of decline， with symptoms gradually relieved and the quality of life improved. Therefore， the treatment effect is considered relatively significant.

[Key words] Chronic gastritis; Helicobacter pylori eradication therapy; Gastrin level; Helicobacter pylori eradication rate; Probiotics

慢性胃炎属于消化内科比较常见的疾病，患者会出现明显的反酸、嗳气、胃疼等症状，对患者的健康以及生活带来较多的不良影响。随着人们的生活水平不断提升，饮食方式也出现了大幅度的变化，有不良饮食习惯的人群越来越多，导致该病呈现出逐渐向年轻化发展的趋势[1]。……