张颖 张娇

【摘 要】目的：研究探讨硝苯地平联合拉贝洛尔治疗妊娠期高血压疾病子痫前期患者的临床效果。方法：将2019年3月至2020年12月在本科室接受治疗的妊娠期高血压疾病子痫前期患者96例作为本次研究的对象，分为对照组和观察组，每组48例。对照组患者给予拉贝洛尔治疗；观察组患者在对照组基础上给予硝苯地平进行治疗。结果：观察组患者的总有效率更佳，两组对比差异具有统计学意义（P<0.05）；观察组患者的血压改善更佳，两组对比差异具有统计学意义（P<0.05）。结论：硝苯地平联合拉贝洛尔治疗妊娠期高血压疾病子痫前期患者的临床效果十分显著，明显改善患者血压，稳定病情，非常具有临床价值，值得推荐。

【关键词】硝苯地平；拉贝洛尔；妊娠期高血压疾病；子痫前期

The clinical effect of nifedipine combined with labetalol in the treatment of patients with hypertension in pregnancy and preeclampsia

ZHANG Ying1，ZHANG Jiao2 1.Department of Cardiovascular Medicine， Ningxia Hui Autonomous Region Peoples hospital， Ningxia Yinchuan 750004， China；2.Department of Obstetrics and gynecology， Ningxia Hui Autonomous Region Peoples hospital， Ningxia Yinchuan 750004， China

【Abstract】Objective： To study the clinical effect of nifedipine combined with labetalol in the treatment of preeclampsia patients with hypertension in pregnancy.Methods： Ninety-six patients with hypertension in pregnancy and preeclampsia who were treated in the undergraduate room from March 2019 to December 2020 were the subjects of this study. They were divided into control group and observation group， each group had 48 cases. Patients in the control group were treated with labetalol； patients in the observation group were treated with nifedipine on the basis of the control group. Results： The total effective rate of patients in the observation group was better， and the difference between the two groups was statistically significant（P<0.05）； the blood pressure of the patients in the observation group improved better， and the difference between the two groups was statistically significant（P<0.05）.Conclusion： The clinical effect of nifedipine combined with labetalol in the treatment of patients with hypertension in pregnancy and preeclampsia is very significant. It can significantly improve the blood pressure of the patients and stabilize the condition. It has very clinical value and is worth of recommendation.

【Key？Words】Nifedipine； Labetalol； Hypertension in pregnancy； Preeclampsia

妊娠期高血壓多发生在妊娠20周以后，临床表现以高血压、蛋白尿为特征，并伴有全身多脏器的损害；严重时出现抽搐、昏迷，脑出血、心力衰竭、弥漫性血管内凝血等，甚至死亡。妊娠期高血压疾病包括妊娠期高血压、子痫前期、子痫、慢性高血压并发子痫前期和慢性高血压。该病严重影响母婴的健康。所以妊娠期高血压应积极预防与治疗，以免引起不良后果影响胎儿及母体健康。如果治疗不及时，可能导致早产难产、胎盘早剥、胎儿生长窘迫等现象发生[1]。关键词：医养结合；老年慢性病；生存质量；本次研究将随机选取2019年3月至2020年12月在本院妇产科联合心血管内科接受治疗的妊娠期高血压疾病子痫前期患者96例作为本次研究的对象，研究探讨硝苯地平联合拉贝洛尔治疗妊娠期高血压疾病子痫前期患者的临床效果，现总结如下。

1 资料与方法

1.1 一般资料

将2019年3月至2020年12月在我院妇产科联合心血管内科接受治疗的妊娠期高血压疾病子痫前期患者96例作为本次研究的对象，分为对照组和观察组，每组48例。……