葛荣晖　史克佳　张海靖　安颖慧

[摘要]目的：探讨在青少年正畸治疗中应用磷硅酸钙钠凝胶制剂的临床效果。方法：选取2017年5月-2019年8月在笔者医院接受正畸治疗的青少年患者78例，根据随机数字表法以及患者自愿原则，将其分为对照组（41例）和研究组（37例），其中对照组给予GC护牙素，研究组在其基础上应用磷硅酸钙钠凝胶制剂。比较两组患者牙釉质脱矿指数（EDI）、菌斑指数（PLI）和脱矿发生率，并评估患者生活质量。结果：治疗后1个月，两组患者EDI、PLI值比较无显著差异（P>0.05），治疗后6个月、12个月，研究组EDI、PLI值显著低于对照组（P<0.05）;治疗后1个月，两组患者脱矿发生率比较无显著差异（P>0.05），治疗后6个月、12个月，研究组脱矿发生率显著低于对照组（P<0.05）;研究组患者口腔健康、自我形象和社会-情感健康分值显著高于对照组（P<0.05），两组功能健康和学校环境分值比较无显著差异（P>0.05）。结论：硅酸钙钠凝胶制剂可较好地抑制青少年正畸治疗患者牙釉质脱矿，促进再矿化的发生，同时有利于维持良好的口腔卫生，提高其生活质量。

[关键词]青少年;正畸治疗;磷硅酸钙钠凝胶制剂;GC护牙素;脱矿指数

[中圖分类号]R783.5    [文献标志码]A    [文章编号]1008-6455（2021）09-0164-03

Effect Analysis of Calcium Sodium Phosphosilicate Gel Preparation in Preventing Enamel Demineralization and Promoting Enamel Remineralization in Orthodontic Treatment of Adolescents

GE Rong-hui，SHI Ke-jia，ZHANG Hai-jing，AN Ying-hui

（Department of Stomatology，People's Hospital of Langfang City，Hebei Province，Langfang 065000，Hebei，China）

Abstract：Objective To study the clinical effects of calcium sodium phosphosilicate gel preparation in orthodontic treatment of adolescents. Methods  Seventy-eight adolescents who underwent orthodontic treatment in the hospital from May 2017 to August 2019 were enrolled. They were divided into control group （41 cases） and study group （37 cases） according to the random number table method and patient voluntary principle. The control group received treatment with GC tooth mouse， while the study group received treatment with calcium sodium phosphosilicate gel preparation based on the treatment of the control group. The enamel demineralization index （EDI）， plaque index （PLI） and incidence of demineralization in the two groups were compared， and patients quality of life was assessed. Results  One month after treatment， there were no significant differences in EDI and PLI between the two groups （P>0.05）. Six and 12 months after treatment， EDI and PLI in the study group were significantly lower than those in the control group （P<0.05）. One month after treatment， there was no significant difference in the incidence of demineralization between the two groups （P>0.05）. Six and 12 months after treatment， the incidence of demineralization in study group was significantly lower than that in control group （P<0.05）. The scores for oral health， self-image and social-emotional health of the study group were significantly higher than those of the control group （P<0.05）， but there were no significant differences in scores for functional health and school environment between the two groups （P>0.05）. Conclusion Calcium sodium phosphosilicate gel preparation can better inhibit demineralization in adolescents undergoing orthodontic treatment， and promote the occurrence of re-mineralization. Meanwhile， it can help the patients maintain good oral hygiene and improve their quality of life.

Key words： adolescent;orthodontic treatment; calcium sodium phosphosilicate gel preparation; GC tooth mouse; demineralization index

据统计，我国牙齿畸形的发病率高达68%，已成为青少年常见的生长发育畸形问题[1]。目前，治疗牙齿畸形最为有效的方法是正畸固定矫正，其治疗效果已经大量研究证实[2]。但固定矫治器治疗周期较长，在治疗过程中，矫治器因与牙面粘接时间较长，且不易清洁，故托槽周围牙釉质容易发生脱矿，从而增加釉质龋发生风险，对青少年的身心健康、学习生活均造成严重影响[3-4]。既往常用的预防正畸牙脱矿的方法包括氟化物、护牙素，其中氟化物因易增加氟牙症致使其临床应用较为局限，后者是一种乳状的牙科护理材料，可较好地预防和治疗牙釉质脱矿[5]。磷硅……