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红细胞输注无效原因分析及解决策略

2021-09-08王秀菊

健康之家 2021年6期

王秀菊

摘要:目的:分析红细胞输注前后的有效性,进一步探讨红细胞输注无效的影响因素及解决策略。方法:选择2019年1~6月全院住院患者作为研究对象,红细胞输注共2 990例,其中外科患者1 223例,内科患者1 767例,采用凝聚胺法测定红细胞输注情况,分析红细胞输注无效的原因,并制定相应的措施。结果:外科红细胞输注无效率为21.7%,内科无效率为23.0%,外科及内科无效率比较,差异无统计意义(P>0.05);单因素及多因素Logistic分析结果表明,输血次数、患有自身免疫系统疾病及红细胞制品贮存时间长为全院住院患者红细胞输注无效发生率的影响因素(P<0.05)。结论:红细胞输注效果在临床上受免疫因素和非免疫因素影响,只有避免这些因素影响,掌握输血指征,合理有效用血,节约血液资源。

关键词:红细胞;输注无效;原因分析;解决策略

Cause analysis and solution strategy of invalid red blood cell transfusion

WANG Xiuju,YANG Weihua,JIANG Shaowei,et al. (DePartment of Blood Transfusion, 940th HosPital of Joint Logistics SuPPort Force Lanzhou City, Gansu Province 730000)

Abstract Objective To analyze the effectiveness of red blood cell transfusion before and after, and to further exPlore the influencing factors and solution strategies of the ineffective red blood cell transfusion. Methods: Selected hosPitalized Patients from January to June 2019 as the research object. A total of 2 990 red blood cell transfusions, including 1 223 surgical Patients and 1 767 internal medicine Patients, were selected for the study of red blood cell transfusion using Polybrene method and red blood cell analysis Reasons for invalid infusion, and develoP corresPonding measures. Results: The effect of red blood cell transfusion is clinically affected by immune factors and non-immune factors; single-factor and multi-factor Logistic analysis results show that: the incidence of ineffective red blood cell transfusion and the number of blood transfusions in hosPitalized Patients, autoimmune system diseases and The long storage time of red blood cell Products is statistically significant (P<0.05). Conclusion: Master the indications for blood transfusion, use blood rationally and effectively, and save blood resources.

Key words Red blood cell, transfusion failure, cause analysis, solution strategy

成分輸血是目前临床重要的治疗手段,红细胞输血在临床输血占有很大比重。红细胞输注是改善机体缺氧状态,已成为临床必不可少的治疗方法。但红细胞的输注在临床上,有时并未达到真正的输血目的,红细胞输注无效已在临床引起高度重视。红细胞输注无效不但耽误患者治疗,并给患者造成经济负担,同时也造成宝贵血液资源的浪费。红细胞输注无效受多种因素影响,现将红细胞输注无效的原因及结果分析如下:

1资料与方法

1.1 一般资料

经统计,我院2019年1~6月全院住院患者中,红细胞输注共2 990例,其中外科患者1 223例,内科患者1 767例。患者男1 751例,女1 239例,年龄31~84岁,平均(57.98±6.71)岁。本研究获得医院医学伦理委员会批准,患者及家属签署知情同意书。

1.2 红细胞输注效果判定标准

根据我国200 ml全血制备的红细胞制剂容量约为150 ml,定为1个单位,以血红蛋白的增加量来衡量。在……

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