胡芬 羊燕群 张均倡 黄秀红

【摘 要】 目的：探究《中药成方制剂》中含干姜方剂的组方规律。方法：基于中医传承辅助平台（V2.5）软件，筛选符合的方剂构建数据库，应用软件集成的数据挖掘方法，对处方中含干姜方剂的主治疾病、证侯、组方配伍等进行分析，并选取高频药对及高频疾病进行药物组合的深度分析。结果：通过131首方剂的分析，得出常用药对17个，主治疾病62种。干姜在不同药对中功效发挥方向不同，在不同疾病中使用规律各异。结论：含干姜的方剂临床应用广泛，其组方规律反应出干姜在治疗不同疾病时的药物组合特点。

【关键词】 干姜;中药成方制剂;组方规律;数据挖掘

【中图分类号】R289   【文献标志码】 A    【文章編号】1007-8517（2021）12-0019-05

Abstract：Objective To explore the Prescription rules of prescriptions containing dried ginger in National Standard for Chinese Patent Drugs.Methods Based on the software of Traditional Chinese Medicine Inheritance Support System （V2.5），the suitable prescriptions were selected to build a database，and the software integrated data mining method was applied to analyze the main diseases，syndromes and compatibility of prescriptions containing dried ginger prescription in the prescription，and high-frequency medicine pairs and high-frequency diseases were selected for in-depth analysis of drug combination.Results Through the analysis of 131 prescriptions，17 commonly used drug pairs were obtained，and 62 kinds of diseases were mainly treated. The action direction of dried ginger is different in different drug pairs，and the direction of effectiveness in different diseases is different.Conclusion The prescription containing dried ginger is widely used in clinical practice，and its Prescription rules reflect the characteristics of drug combination in the treatment of different diseases.

Keywords：Dried Ginger;National Standard for Chinese Patent Drugs（NSCPD）;Prescription Rule;Data Mining

干姜是姜科植物姜Zingiber officinale Rosc.的干燥根茎，别名白姜、均姜。干姜味辛，性热，归脾、胃、肾、心、肺经，具有温中散寒、回阳通脉、温肺化饮的功效，用于脘腹冷痛、呕吐泄泻、肢冷脉微、寒饮喘咳[1]。干姜药用价值高，在历代本草《神农本草经》《本草纲目》《本草经疏》等均有记载。干姜作为药食同源的中药，广泛用于日常生活和临床用药中。干姜具有多重药理作用和保健功能，极具研究价值，值得深入开发利用。《中华人民共和国卫生部药品标准—中药成方制剂》（以下简称为《中药成方制剂》收录的中成药有4000多种，其不仅规范了中成药的质量标准，也代表了中成药在临床应用的主流[2]。本研究旨在对含有干姜的成方制剂进行数据挖掘分析，探索其组方规律，为临床医生提供直观的用药规律，为新药开发提供参考。……