介入微弹簧圈栓塞术治疗颅内动脉瘤的临床效果探讨
2021-06-15刘欣民张清平宋伟健魏强国
刘欣民 张清平 宋伟健 魏强国



【摘要】 目的:分析介入微弹簧圈栓塞术治疗颅内动脉瘤的临床效果。方法:选取2017年1月-2019年9月本院收治的颅内动脉瘤患者115例,对其进行介入微弹簧圈栓塞术,观察并对比患者栓塞的临床效果,栓塞程度,术前及术后1、7 d的WBC、CRP情况,及并发症情况。结果:115例患者,完全栓塞86例,次全栓塞26例,不完全栓塞3例。动脉瘤<4.0 mm患者的完全栓塞率最高,且<4.0 mm患者与≥4.0 mm患者栓塞效果对比,差异有统计学意义(P<0.05)。所有患者术后WBC、CRP水平均优于术前,差异均有统计学意义(P<0.05)。115例患者中,5例出现术中动脉瘤破裂,1例出现对比剂外溢,1例出现一过性血压升高,接受手术治疗后1个月内,2例患者死亡。结论:颅内动脉瘤患者进行介入微弹簧圈栓塞术具有创伤小、并发症较少、治疗后恢复速度较快等优点,值得临床推广使用。
【关键词】 微弹簧圈栓塞术 颅内动脉瘤 介入
Clinical Efficacy of Interventional Micro Coil Embolization in the Treatment of Intracranial Aneurysms/LIU Xinmin, ZHANG Qingping, SONG Weijian, WEI Qiangguo. //Medical Innovation of China, 2021, 18(12): -150
[Abstract] Objective: To analyze the clinical efficacy of interventional micro coil embolization in the treatment of intracranial aneurysms. Method: A total of 115 patients with intracranial aneurysms treated in our hospital from January 2017 to September 2019 were selected and given interventional micro coil embolization, and the clinical effect, the degree of embolization, the levels of WBC and CRP before operation and 1 and 7 d after operation, the complications of two groups were observed and compared. Result: 115 patients, 86 cases of complete embolism, 26 cases of subtotal embolization, 3 cases of incomplete embolism, patients with aneurysms <4.0 mm had the highest complete embolization rate, and the difference between <4.0 mm patients and ≥4.0 mm patients in the embolization effect was statistically significant (P<0.05). After treatment, The levels of WBC and CRP of all patients after operation were significantly better than those of before operation (P<0.05). Among 115 patients, 5 patients had aneurysm rupture, 1 patient had contrast agent overflow, 1 patient had transient hypertension and 2 patients died 1 month after operation. Conclusion: Interventional micro coil embolization for intracranial aneurysms has the advantages of less trauma, fewer complications and faster recovery after treatment, it is worthy of clinical application.
[Key words] Micro coil embolization Intracranial aneurysm Intervention
First-authors address: Huazhong University of Science and Technology Union Shenzhen Hospital, Shenzhen 518052, China
doi:10.3969/j.issn.1674-4985.2021.12.035
顱内动脉瘤亦被称为脑动脉瘤,是指人体颅内动脉的局部损伤,导致血管壁的异常膨出[1]。颅内动脉瘤是一种脑血管疾病,并不是肿瘤,不会扩散,也不需要做放疗和化疗[2]。但是脑动脉瘤破裂后,会造成生命危险[3],给家庭和社会带来沉重负担。其中未破裂动脉瘤一般不会有任何症状,或患者临床症状比较轻微,如轻微头痛、眼睑下垂、视物重影等;破裂脑动脉瘤会发生渗血或出血的情况[4]。颅内动脉瘤发病较急,从发病到救治的时间长短决定了患者的治疗效果[5]。然而,每个患者动脉瘤的形态、位置以及大小都是不一样的,这就要结合具体情况制定治疗方案,预防瘤体破裂,避免发生脑出血是治疗动脉瘤的治疗原则[6]。近些年来,神经介入放射学的发展越来越成熟,目前介入微弹簧圈栓塞术治疗颅内动脉瘤患者已经非常普遍了[7]。此次研究选取2017年1月-2019年9月本院收治的颅内动脉瘤患者共115例,对其进行介入微弹簧圈栓塞术治疗,部分予支架辅助栓塞,现报道如下。
1 资料与方法
1.1 一般资料 选取2017年1月-2019年9月本院收治的颅内动脉瘤患者115例。……
