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甲状腺癌患者超声特征与颈部淋巴结转移的关系探究

2021-06-15王丽

中国医学创新 2021年12期

王丽

【摘要】 目的:探究甲狀腺癌患者超声特征与颈部淋巴结转移的关系。方法:回顾性分析2017年9月-2020年9月本院确诊的甲状腺癌患者186例的超声特征,其中90例(125枚癌结节)发生颈部淋巴结转移设为转移组,96例(103枚癌结节)未发生颈部淋巴结转移设为未转移组,分析甲状腺超声各参数与颈部淋巴结转移的关系。结果:以病理诊断为金标准,超声诊断的灵敏度为93.33%(112/120),特异度为87.96%(95/108),准确率为90.79%(207/228),阳性预测值为89.60%(112/125),阴性预测值为92.23%(95/103)。两组结节直径、纵横比、微钙化、内部血流、内部回声、Vmax、RI比较,差异均有统计学意义(P<0.05);两组结节形态、边界比较,差异均无统计学意义(P>0.05)。其中转移组结节直径≥1.5 cm、纵横比≥1、有微钙化、内部血流丰富、内部回声不均匀发生率均高于未转移组(P<0.05),Vmax、RI均高于未转移组(P<0.05)。结论:超声检查甲状腺癌颈部淋巴结转移具有较高的灵敏度、准确度,结果较为可靠,特别是当出现结节直径≥1.5 cm、纵横比≥1、有微钙化、内部血流丰富、内部回声不均匀、Vmax增大、RI>0.7时,应高度怀疑发生颈部淋巴结转移的可能。

【关键词】 甲状腺癌 超声特征 颈部淋巴结转移

Relationship between Ultrasound Features and Cervical Lymph Node Metastasis in Patients with Thyroid Cancer/WANG Li. //Medical Innovation of China, 2021, 18(12): -142

[Abstract] Objective: To explore the relationship between ultrasound features and cervical lymph node metastasis in patients with thyroid cancer. Method: A total of 186 cases of thyroid cancer patients diagnosed in our hospital from September 2017 to September 2020 were retrospectively analyzed. Among them, 90 cases (125 cancer nodules) with cervical lymph node metastasis were set as metastasis group, 96 cases (103 cancer nodules) without cervical lymph node metastasis were set as non metastasis group, the relationship between ultrasound features and cervical lymph node metastasis was analyzed. Result: The sensitivity, specificity, accuracy, positive predictive value and negative predictive value of ultrasound were 93.33% (112/120), 87.96% (95/108), 90.79% (207/228), 89.60% (112/125) and 92.23% (95/103) respectively. The nodule diameter, aspect ratio, microcalcification, internal blood flow, internal echo, Vmax and RI of two groups compared, there were significant differences (P<0.05). The nodule shape and boundary of two groups were not statistically significant (P>0.05). The incidences of nodule diameter ≥1.5 cm, aspect ratio ≥1, microcalcification, rich internal blood flow and uneven internal echo in metastasis group were higher than those in non metastasis group (P<0.05), Vmax and RI were higher than those in non metastasis group (P<0.05). Conclusion: Ultrasound examination of cervical lymph node metastasis of thyroid cancer has high sensitivity and accuracy, the results are reliable, especially when the nodule diameter ≥1.5 cm, aspect ratio ≥1, microcalcification, rich internal blood flow, uneven internal echo, Vmax increase, RI >0.7, the possibility of cervical lymph node metastasis should be highly suspected.

[Key words] Thyroid cancer Ultrasonic characteristics Cervical lymph node metastasis

First-authors address: Fengcheng Central Hospital, Fengcheng 118100, China

doi:10.3969/j.issn.1674-4985.2021.12.033

甲狀腺癌为临床上较为常见的恶性肿瘤,主要发生于甲状腺中的被膜处或背侧,临床表现为呼吸或吞咽困难、声音嘶哑等[1-4]。虽然进程相对较慢、侵袭性小,但转移率高达50%,且复发病灶常累及淋巴结,严重影响患者预后,颈部淋巴结是甲状腺癌常发生的转移部位。因此,及时发现甲状腺癌的转移情况至关重要[5-8]。目前,超声检查作为简单、便捷、无创、显示性较好的检查手段,已被临床医生们广泛应用。本文通过分析甲状腺癌患者颈部淋巴结的超声特征,研究其与颈部淋巴结的关系,以期为临床治疗制定合理、规范的方案,现报道如下。

1 资料与方法

1.1 一般资料 回顾性分析2017年9月-2020年9月在本院确诊的甲状腺癌患者186例的超声特征。……

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