苏海兰，郑梅霞，陈宏, 李永，周贵斌，朱育菁

摘要：探究野生与种植博落回不同部位的原阿片碱、别隐品碱、血根碱、白屈菜红碱和总生物碱的含量差异。采集明溪野生、明溪种植、光泽野生的博落回样品，利用HPLC方法对各部位原阿片碱、别隐品碱、血根碱、白屈菜红碱和总生物碱含量进行测定，并利用SPSS 180进行数据的统计与分析。研究结果表明，野生与种植博落回除茎部中的原阿片碱含量和叶部中的别隐品碱外，其他生物碱含量差异不显著。不同的生长条件下博落回同一部位的生物碱含量差异较小，而同一生长条件下博落回不同部位的生物碱含量差异较大，其中根部各生物碱含量更为丰富。

关键词：博落回;生物碱;野生;种植;不同部位

中图分类号：R 2841 文献标志码：A文章编号：0253-2301（2021）02-0032-05

DOI： 1013651/jcnkifjnykj202102006

Analysis on Alkaloid Content in Different Parts of the Wild and the Planted Macleaya Cordata

SU Hailan1， ZHENG Meixia1， CHEN Hong1， LI Yong2， ZHOU Guibin2， ZHU Yujing1*

（1. Institute of Agricultural Biological Resources， Fujian Academy of Agricultural Sciences， Fuzhou，

Fujian 350003， China; 2. Fujian South Pharmaceuticals Co.， Ltd.， Sanming， Fujian 365200， China）

Abstract： In order to investigate the differences in the content of fumarine， allocryptopine， sanguinarine， chelerythrine and total alkaloids in different parts of the wild and the planted Macleaya cordata， the samples were collected from the wild and the planted Macleaya cordata in Mingxi County and the wild Macleaya cordata in Guangze County. Then， the contents of fumarine， allocryptopine， sanguinarine， chelerythrine and total alkaloids in each part were determined by HPLC method， and SPSS 180 was used for the data statistics and analysis. The results showed that there was no significant difference in the contents of other alkaloids between the wild and the planted Macleaya cordata except for the contents of fumarine in the stem and allocryptopine in the leaves. Under different growth conditions， the content of alkaloids in the same part of Macleaya cordata had little difference， while under the same growth condition， the content of alkaloids in different parts of Macleaya cordata had great difference， among which the content of alkaloids in the root was more abundant.

Key words： Macleaya cordata; Alkaloids; Wild; Planting; Different parts

博落回Macleaya cordata Wild.R.Br.系罌粟科博落回属多年生植物，在我国分布广泛＼[1＼]。博落回属植物具有杀虫、止痒、清热、解毒等功效，在临床上用于治疗肺炎、肝炎和皮肤病等，还有抗肿瘤活性作用＼[2-4＼]。明确野生与种植条件下不同部位的生物碱含量差异，对于增加博落回的利用效率，满足市场供给需求具有重要意义。博落回属植物含有多种化学成分＼[5＼]，现代药理研究表明其生物碱为主要的活性成分＼[6＼]。生物碱是由氨基酸衍生而来的低分子量、含氮且不包括氨基酸、蛋白质、核苷、叶啉和胆碱甲胺等开链的简单脂肪胺的有机化合物。作为一类重要的次生代谢产物，生物碱具有抵抗食草动物和抗病原体的作用。……