王守福 刘洪秀 王栋

摘 要 目的：探讨罗哌卡因浸润麻醉联合地佐辛静脉麻醉在食管癌根治术中的效果。方法：随机选取我院收治的110例食管癌根治手术患者将其随机分为观察组和对照组各55例。对照组给予罗哌卡因浸润麻醉，观察组给予罗哌卡因浸润麻醉联合地佐辛静脉麻醉。观察不同方法对两组患者的麻醉效果、生活质量以及不良反应发生率的影响。结果：观察组的麻醉效果、生活质量优于对照组；观察组的不良反应发生率比对照组低（P<0.05）。结论：罗哌卡因浸润麻醉联合地佐辛静脉麻醉在食管癌根治术中的疗效显著，可有效提升患者生活质量，具有临床应用价值。

关键词 食管癌根治术 罗哌卡因 浸润麻醉 地佐辛 静脉麻醉

中图分类号：R971.2； R614.32 文献标志码：A 文章编号：1006-1533（2021）23-0055-03

Effect of ropivacaine infiltration anesthesia combined with dezocine intravenous anesthesia in radical resection of esophageal cancer

WANG Shoufu1， LIU Hongxiu2， WANG Dong2（1. Department of Human Anatomy； 2. Anesthesia Teaching and Research Section， Heze Medical College， Heze 274000， China）

ABSTRACT Objective： To investigate the effect of ropivacaine infiltration anesthesia combined with dezocine intravenous anesthesia in radical resection of esophageal cancer. Methods： One hundred and ten patients with esophageal cancer undergoing radical surgery were randomly selected and divided into an observation group and a control group with 55 cases each. The control group was given ropivacaine infiltration anesthesia， and the observation group was given ropivacaine infiltration anesthesia combined with dezocine intravenous anesthesia. The effects of different methods on the anesthesia effect， quality of life and incidence of adverse reactions of the patients were observed. Results： The anesthesia effect and quality of life were much better while the incidence of adverse reactions was lower in the observation group than the control group （P<0.05）. Conclusion： Ropivacaine infiltration anesthesia combined with dezocine intravenous anesthesia is effective in radical surgery of esophageal cancer， can effectively improve the quality of life of patients， and has clinical application value.

KEY WORDS radical resection of esophageal cancer； ropivacaine； infiltration anesthesia； dezocine； intravenous anesthesia

食管癌又叫食道癌，是較为常见的消化道肿瘤，是发生在食管上皮组织的恶性肿瘤，食管癌根治术是一种创伤较为严重的开胸手术，患者全麻术后通常会有明显的疼痛感，易发生躁动，极其影响患者的术后恢复[1]。相关研究显示[2]，术后疼痛是引起全麻患者恢复期出现应激反应的主要因素，镇痛药可以减少患者的应激反应，但是会使患者出现苏醒时间延长等不良反应。罗哌卡因是酰胺类麻药，有麻醉、镇痛之功效，有研究发现[3-4]，罗哌卡因对术后镇痛有很好的效果，而作为强效止痛药的地佐辛，能有效缓解患者术后疼痛，且对患者的肠胃以及呼吸系统的影响较小。本研究主要探讨了罗哌卡因浸润麻醉与地佐辛静脉麻醉联合应用在食管癌根治术中的效果。……