脑出血患者不同出血部位与睡眠的相关性研究
2020-12-23申志远
申志远

摘要 目的:分析睡眠與脑出血患者出血部位不同的相关性。方法:选取2017年7月至2019年7月谷城县人民医院收治的脑出血患者104例作为研究对象,对患者的病例资料进行分析,比较患者空腹血糖、糖化血红蛋白和血脂等情况,使用匹兹堡睡眠质量指数(PSQI)量表对患者发病前后的睡眠时间和睡眠质量进行评估,并通过Logistic回归分析不同脑出血部位与睡眠之间的联系。结果:104例脑出血患者中,56例为基底节出血,占比53.85%;31例为丘脑出血,占比29.81%;27例睡眠时间<7 h,占比25.96%,43例睡眠时间为7~8 h,占比41.35%,34例睡眠时间>8 h,占比32.69%。Logistic回归分析表明,睡眠质量差可增加丘脑出血的风险(OR=2.392,95%CI:1.135~5.017);经常午休可增加脑叶出血的风险(OR=12.138,95%CI:1.534~110.536),睡眠时间<7 h可增加脑干出血的风险(OR=9.326,95%CI:1.391~60.314)。结论:睡眠时间不足与脑干出血有关,睡眠质量差与丘脑出血有关,经常午休与脑叶出血有关。
关键词 脑出血;不同出血部位;睡眠;相关性
Abstract Objective:To analyze the correlation between sleep and bleeding site in patients with intracerebral hemorrhage.Methods:A total of 104 patients with intracerebral hemorrhage from july 2017 to july 2019 in gu cheng county people′s hospital as the study object,analyzed the patient′s case data,compared the patients′ fasting blood glucose,glycosylated hemoglobin and blood lipids,and used the pittsburgh sleep quality index(PSQI)scale to evaluate the sleep time and sleep quality before and after onset,and analyzed the association between different cerebral hemorrhage sites and sleep by Logistic regression.Results:The 104 patients with cerebral hemorrhage,56 had basal ganglia hemorrhage,accounting for 53.85%; 31 had thalamus hemorrhage,accounting for 29.81%; 27 had less than 7 h sleep,accounting for 25.96%; 43 had 7~8 h sleep,accounting for 41.35%; 34 had more than 8 h sleep,accounting for 32.69%.Logistic regression analysis showed that poor sleep quality could increase the risk of thalamic hemorrhage(OR=2.392,95% CI:1.135~5.017); frequent lunch break could increase the risk of lobar hemorrhage(OR=12.138,95% CI:1.534~110.536),and sleep time<7 h could increase the risk of brainstem hemorrhage(OR=9.326,95% CI:1.391~60.314).Conclusion:Lack of sleep time is related to brainstem hemorrhage,poor sleep quality is related to thalamus hemorrhage,frequent lunch break is related to lobar hemorrhage.
Keywords Cerebral hemorrhage;Different bleeding sites;Sleep;Correlation
中图分类号:R743.3;R338.63文献标识码:Adoi:10.3969/j.issn.2095-7130.2020.10.015
脑出血是指原发性脑内出血,在脑部疾病中发病率较高,且发病急、危害大,是一种较为严重的脑血管疾病[1]。近年来,我国脑出血发病率呈现出日趋上升的趋势。但关于睡眠与不同脑部出血的相关性暂无过多研究,本研究对104例脑出血患者进行探讨,试分析睡眠与脑出血患者出血部位之间的相关性,并找出引发脑出血的潜在风险,现报道如下。
1 资料与方法
1.1 一般资料 选取2017年7月至2019年7月谷城县人民医院收治的脑出血患者104例作为研究对象,其中男67例,女37例;年龄33~79岁,平均年龄(55.1±2.6)岁。
1.2 纳入标准 所有研究对象均符合国际脑出血诊断标准,并经我院CT等影像学检查确诊;经告知后患者及家属均同意参与本研究,并签署相关文件。
1.3 排除标准 外伤性脑出血;肝肾器官严重受损者;精神意识不清晰,无法正常交流者。……
