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曲美他嗪治疗冠心病伴心力衰竭临床分析

2020-10-13高丽丽

中外医疗 2020年22期
关键词:曲美他嗪心力衰竭治疗效果

[摘要] 目的 分析曲美他嗪治疗冠心病伴心力衰竭临床治疗效果。方法 方便抽取2018年6月—2019年6月在该院接受治疗急性心肌梗死患者78例为研究对象,根据其住院先后顺序从1~78编号,再按等差数列首项为1,公差为2的方式将78例患者平均分為两组,即对照组与实验组,两组患者均为39例。对照组患者行常规治疗,实验组在常规治疗基础上予以曲美他嗪治疗,对比两组患者治疗效果和患者血流情况。结果 实验组患者治疗总有效率(97.43%)高于对照组(79.48%)(χ2=6.210,P<0.05);实验组患者左室射血分数(LVEF)、左室舒张末期内径 (LVEDD) 和左心室缩短分数 (FS)分别为(44.61±5.34)%、(52.36±6.98)mm、(32.81±7.64)%,对照组患者左室射血分数(LVEF)、左室舒张末期内径 (LVEDD) 和左心室缩短分数 (FS)分别为(34.68±5.39)%、(58.21±5.34)mm、(25.36±5.94)%,差异有统计学意义(t=10.375、5.397、5.364,P<0.05)。 结论 曲美他嗪治疗冠心病伴心力衰竭效果优于常规治疗,能够提高治疗总有效率,提高患者左室射血分数(LVEF)和左心室缩短分数 (FS),使患者左室舒张末期内径处于正常水平。

[关键词] 曲美他嗪;冠心病;心力衰竭;治疗效果;血流情况

[中图分类号] R541          [文献标识码] A          [文章编号] 1674-0742(2020)08(a)-0107-03

Clinical Analysis of Trimetazidine in the Treatment of Coronary Heart Disease with Heart Failure

GAO Li-li

Department of Cardiology, Lingcheng People's Hospital, Dezhou, Shandong Province, 253500 China

[Abstract] Objective To analyze the clinical effect of trimetazidine in the treatment of coronary heart disease with heart failure. Methods Seventy-eight patients with acute myocardial infarction who were treated in the hospital from June 2018 to June 2019 were conveniently selected as the research subjects. They were numbered from 1-78 according to the order of their hospitalization, and then the first item in the arithmetic sequence was 1 and the tolerance was 2, the 78 patients were divided into two groups, namely the control group and the experimental group, with 39 patients in both groups. Patients in the control group received conventional treatment, while experimental group was treated with trimetazidine on the basis of routine care. The treatment effect and blood flow of patients in the two groups were compared. Results The total effective rate of treatment in the experimental group (97.43%) was higher than that in the control group (79.48%)(χ2=6.210, P<0.05); patients in the experimental group had left ventricular ejection fraction (LVEF), left ventricular end diastolic diameter (LVEDD), left ventricular shortening fraction (FS) was (44.61±5.34)%, (52.36±6.98)mm, and (32.81±7.64)%. Patients in the control group had left ventricular ejection fraction (LVEF) and left ventricular end-diastolic diameter(LVEDD) and left ventricular shortening fraction (FS) were (34.68±5.39)%, (58.21±5.34)mm, (25.36±5.94)%,the difference was statistically significant (t=10.375, 5.397, 5.364, P<0.05). Conclusion Trimetazidine is more effective than conventional treatment for coronary heart disease with heart failure. It can improve the total effective rate of treatment, increase the left ventricular ejection fraction (LVEF) and left ventricular shortening fraction (FS), and make the patient's left ventricular end-diastole. The neck is at a normal level.

综上所述,曲美他嗪治疗冠心病伴心力衰竭效果优于常规治疗,能够提高治疗总有效率,提高患者左室射血分数(LVEF)和左心室缩短分数 (FS),使患者左室舒张末期内径处于正常水平,值得在临床上推广。

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(收稿日期:2020-05-09)

[作者简介] 高丽丽(1983-),女,山东德州人,本科,主治医师,研究方向:心内科。

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