董格

【摘要】目的：分析胎儿宫内生长受限采用低分子肝素治疗的效果及不良结局情况。方法：随机选取本院2018年2月-2019年6月期间收治的72例胎儿宫内生长受限产妇进行此次研究，按照随机抽签法均分两组，各36例。其中，给予传统治疗的为参照组，在此基础上给予心低分子肝素治疗的为研究组，比较两组患者的治疗效果和不良结局。结果：研究组治疗后脐血流指标和不良妊娠结局都低于参照组，新生儿身高体重值高于参照组，结果有显著差异（P<0.05）。结论：综上所述，使用低分子肝素进行胎儿宫内生长受限的治疗，能够促进胎儿在子宫内的发育，提高新生儿出生后的身长、体重等指标，有利于儿童日后的长久发展，同时，能够在极大程度上降低出现不良妊娠结局的概率，其治疗效果明显、安全性高，具有应用推广价值。

【关键词】胎儿宫内生长受限;低分子肝素;治疗效果

【中图分类号】R714.5 【文献标识码】A

[Abstract] Objective：To analyze the effect and adverse outcome of low molecular weight heparin in the treatment of fetal intrauterine growth restriction. Methods：72 cases of pregnant women with intrauterine growth restriction in our hospital from February 2018 to June 2019 were randomly selected and randomly divided into two groups， 36 cases in each group. Among them， the traditional treatment for the reference group， on this basis to give low molecular weight heparin treatment for the study group， compared the treatment effect and adverse outcomes of the two groups of patients. Results：after treatment， the umbilical blood flow index and adverse pregnancy outcome of the study group were lower than those of the reference group， and the neonatal height and weight value was higher than that of the reference group， the results were significantly different （P < 0.05）. Conclusion：To sum up， the use of low molecular weight heparin in the treatment of fetal intrauterine growth restriction can promote the development of the fetus in the uterus， improve the length and weight of the newborn after birth， which is conducive to the long-term development of children in the future. At the same time， it can greatly reduce the probability of adverse pregnancy outcomes. The treatment effect is obvious， the safety is high， and it has application promotion price Value.

[Key words] intrauterine growth restriction; low molecular weight heparin; therapeutic effect

胎兒宫内生长受限是一种较为常见的情况，导致这种情况发生的原因包括孕妇宫内感染、营养不良、出现合并症等，使得胎儿生长潜能的决定性遗传因素丧失，适得其身量不足、体重过轻，对妊娠的结局造成影响，引发新生儿窘迫、窒息、死亡等不良情况，并且还会对胎儿的长期生长发育造成影响。就以往的临床经验分析，胎儿生长受限有不同的病因类型，在治疗上要根据其类型的不同尽早治疗。通过补充微元素、吸氧、营养支持、注射葡萄糖、氨基酸等对微循环情况进行改善，这种治疗方法在一定程度上对胎盘的功能性起到了维持作用，但其治疗效果并不完善，有些患者在接受治疗后没有得到较好的效果。……