王琦 刘宇

【摘要】 目的 探究对局灶性脑白质损伤早产儿实施磁共振检查（MR）诊断的效果。方法 随机抽取20例局灶性脑白质损伤早产儿为实验组， 另抽取20例局灶性脑白质损伤足月儿为对照组， 对两组均实施MR诊断， 对比两组影像学表现。结果 两组患儿经常规MR T1WI、T2WI序列扫描显示， T1WI可见高信号， T2WI可见低信号或不表现为低信號， DWI扫描显示可见等信号、高信号， 磁敏感加权成像（SWI）扫描显示可见低信号、高信号。两组患儿均存在点状损伤且均为混合型， 组间比较差异无统计学意义（P>0.05）。线状损伤常见于半卵圆中心及侧脑室体旁， 实验组线状损伤25.0%多于对照组的0， 差异有统计学意义（P<0.05）;簇状损伤常见于侧脑室前后角， 对照组簇状损伤50.0%多于实验组的10.0%， 差异有统计学意义（P<0.05）。结论 对局灶性脑白质损伤早产儿实施MR诊断切实有效， 可为医师分析病情提供依据。

【关键词】 局灶性脑白质损伤;早产儿;足月儿

DOI：10.14163/j.cnki.11-5547/r.2020.22.009

MR diagnosis of punctate white matter lesions in premature infants   WANG Qi， LIU Yu. Sujiatun District Central Hospital， Shenyang 110101， China

【Abstract】 Objective   To investigate the effect of magnetic resonance （MR） in diagnosis of punctate white matter lesions in premature infants. Methods   There were 20 premature infants with punctate white matter lesions as the experimental group， and 20 full-term infants with punctate white matter lesions as the control group. MR diagnosis was performed and the imaging performance of the two groups was compared. Results   The conventional MR T1WI and T2WI sequence scans of the two groups showed that T1WI showed high signals， and T2WI showed low signals or did not show low signals. DWI scan showed visible equal signal and high signal， and magnetic sensitive weighted imaging （SWI） scan showed visible low signal and high signal. Both groups had punctate injuries and were all mixed， and there was no statistically significant difference between the two groups （P>0.05）. Linear injury was common in the center of the semi-oval and the lateral ventricle. The proportion of linear injury 25.0% of the experimental group was more than that of the control group 0， and the difference was statistically significant （P<0.05）. Cluster-like injuries were common in the anterior and posterior horns of the lateral ventricle. The proportion of cluster-like injuries 50.0% of the control group was more than that of the experimental group 10.0%， and the difference was statistically significant （P<0.05）. Conclusion   MR diagnosis of premature infants with punctate white matter lesions is practical and effective， which can provide basis for doctors to analyze the condition.

【Key words】 Punctate white matter lesions; Premature infants; Full-term infants

局灶性脑白质损伤属于临床患病率较高的脑白质损伤性疾病， 主要是由于气体交换和脑供血障碍所致[1]， 若治疗不及时， 大部分患儿可出现脑瘫、认知障碍等后遗症， 故尽早给予其诊断和治疗尤为重要[2]。影像学检查是诊断上述疾病的有效手段， 本院对局灶性脑白质损伤早产儿实施MR诊断取得了较好的效果， 报告如下。

1 资料与方法

1. 1 一般资料 随机抽取2016年1月～2019年1月本院收治的20例局灶性脑白质损伤早产儿为实验组， 另抽取20例局灶性脑白质损伤足月儿为对照组。实验组日龄1～11 d， 平均日龄（6.68±4.73）d;男11例（55.0%）， 女9例（45.0%）;孕周33～36周， 平均孕周（35.24±0.82）周。对照组患儿日龄1～12 d， 平均日龄（7.75±5.42）d;男12例（60.0%）， 女8例（40.0%）;孕周39～41周， 平均孕周（39.68±0.84）周。两组一般资料比较差异无统计学意义（P>0.05）， 具有可比性。

1. 2 方法 对所有受检者均实施……