马立如

【摘要】 目的：探析中成药所致不良反应的相关原因，并分析有效预防措施对临床合理用药的指导作用。方法：选取2017年1月-2019年12月在笔者所在医院接受中成药治疗的110例患者作为研究对象，未接受干预措施的为A组（2017年1月-2018年10月）55例，分析其出现中成药用药不良反应患者的临床资料，从患者年龄、药品剂型、药品品种等方面，对患者发生中成药用药不良反应的原因进行分析，并于2018年11月在笔者所在医院对B组（2018年11月-2019年12月）55例患者实施干预措施，比较两组患者中成药所致不良反应发生率、患者满意度、医患纠纷的发生率。结果：B组中成药所致不良反应发生率、医患纠纷发生率低于A组，患者满意度高于A组，差异均有统计学意义（P<0.05）。结论：对中成药所致不良反应情况给予有效的干预措施，可降低不良反应发生率，促进医患关系的和谐发展。

【关键词】 中成药 不良反应 预防措施 合理用药 指导作用

doi：10.14033/j.cnki.cfmr.2020.16.068 文献标识码 B 文章编号 1674-6805（2020）16-0-03

Analysis of the Causes of Adverse Reactions of Chinese Patent Medicine and the Guiding Effect of Preventive Measures on Clinical Rational Drug Use/MA Liru. //Chinese and Foreign Medical Research， 2020， 18（16）： -168

[Abstract] Objective： To explore the related causes of adverse reactions caused by Chinese patent medicine， and to analyze the guiding role of effective preventive measures in clinical rational drug use. Method： From January 2017 to December 2019， 110 patients who received Chinese patent medicine treatment in the hospital of the author were selected as the research objects， and 55 patients in group A （January 2017 to October 2018） who did not receive the intervention measures were selected. The clinical data of the patients with adverse drug reactions of Chinese patent medicine were analyzed from the aspects of patient age， drug dosage form， drug variety， etc， The causes of adverse reactions of Chinese patent medicine were analyzed. In November 2018， 55 patients in group B （November 2018 December 2019） were intervened in our hospital. The adverse reactions， patient satisfaction and the incidence of medical disputes were compared between the two groups. Result： The incidence of adverse reactions and doctor-patient disputes in group B was lower than that in group A， and the patients satisfaction was higher than that in group A， the differences were statistically significant （P<0.05）. Conclusion： The adverse reactions caused by Chinese patent medicine can be given effective intervention measures， reduce the incidence of adverse reactions， and promote the harmonious development of doctor-patient relationship.

[Key words] Chinese patent medicine Adverse reactions Preventive measures Rational use of drugs Guiding role

First-authors address： Beijing Miyun District Hospital， Beijing 101500， China

中成藥是指以中草药为原料，经加工形成的各种中药制品[1]。其药量配比随患者的病状变化，故临床中难以准确地把控药物的配比，从而造成不良反应，如过敏，胸闷心悸等[2]。我国近年来不良反应发生率逐步攀升，不利于患者的健康，因此必须探析中成药不良反应的原因并提出对策，以保障患者的规范用药[3]。笔者所在医院在2018年实施有效的中成药不良反应预防措施，降低了药品不良反应的发生率。因此，本研究基于2017年1月-2019年12月在笔者所在医院就诊的110例患者的临床资料，探析了中成药不良反应的原因及预防措施对合理用药的指导作用，现报道如下。……