周小琴　郑瑛瑛

【摘要】 目的：探究中重度宫腔粘连（IUA）分离术后运用Foley球囊导尿管联合透明质酸钠预防再粘连的效果。方法：选取2014年4月-2019年5月笔者所在医院收治的60例中重度IUA的患者作为本次研究对象，根据术后防粘连方法为试验组和对照组，每组30例，其中对照组采用宫内节育器联合透明质酸钠进行治疗，试验组采用Foley球囊导尿管联合透明质酸钠进行治疗，研究对比两组空腔再粘连情况、临床疗效及月经情况。结果：经过治疗后，试验组再粘连率显著低于对照组（P<0.05）;试验组总治疗有效率显著高于对照组（P<0.05）;试验组月经恢复良好率高于对照组（P<0.05）。结论：使用球囊支架治疗效果明显优于放置宫内节育器联合透明质酸钠，能显著降低宫腔再粘连发生率，有利于月经恢复正常，值得在临床治疗中推广。

【关键词】 宫腔粘连分离术 Foley球囊导尿管 透明质酸钠 宫内节育器

doi：10.14033/j.cnki.cfmr.2020.21.053 文献标识码 B 文章编号 1674-6805（2020）21-0-03

Effect of Foley Balloon Catheter Combined with Sodium Hyaluronate on Prevention of Readhesion after Separation of Moderate and Severe Intrauterine Adhesions/ZHOU Xiaoqin， ZHENG Yingying. //Chinese and Foreign Medical Research， 2020， 18（21）： -131

[Abstract] Objective： To explore the effect of Foley balloon catheter combined with Sodium Hyaluronate in the prevention of readhesion after separation of moderate and severe intrauterine adhesions. Method： From April 2014 to May 2019， 60 patients with moderate or severe IUA were selected as the study objects. According to the method of postoperative anti adhesion， the patients were divided into the experimental group and the control group， 30 cases in each group. The control group was treated with intrauterine device （IUD） and Sodium Hyaluronate， and the experimental group was treated with Foley balloon catheter and Sodium Hyaluronate. The status of cavity reattachment， clinical effect and menstruation were compared in two groups. Result： After treatment， the rate of readhesion in the experimental group was significantly lower than that in the control group （P<0.05）. The total effective rate in the experimental group was significantly higher than that in the control group （P<0.05）. The normal rate of menstruation in the experimental group was significantly higher than that in the control group， and the abnormal rate of menstruation was significantly lower than that in the control group （P<0.05）. Conclusion： The therapeutic effect of Foley balloon catheter is better than that of IUD placement combined with Sodium Hyaluronate. It can reduce the incidence of intrauterine adhesions， and is beneficial to the recovery of menstruation.

[Key words] Intrauterine adhesions separation Foley balloon catheter Sodium Hyaluronate IUD

First-authors address： Ninety-five Hospital of the Peoples Liberation Army， Putian 351100， China

宫腔粘连（intrauterine adhesions，IUA）是妇科常见宫腔疾病，是子宫内膜基底损伤后导致宫腔部分或完全闭塞形成的疾病。采用宫腔镜可以观察宫腔形态，了解粘连的部位、程度等，因此宮腔镜是宫腔粘连的诊断金标准。临床上治疗该病主要采取手术治疗，其疗效可靠，但若不能采取有效的预防措施，极易再次发生粘连，影响月经、妊娠等，严重影响生殖和心理健康，因此采取有效的手段预防再粘连对患者显得尤为重要[1]。本文旨在探究运用Foley球囊导尿管联合透明质酸钠预防宫腔粘连分离术再粘连的效果。

1 资料与方法

1.1 一般资料

选取2014年4月-2019年5月笔者所在医院收治的60例中重度IUA的患者作为本次研究对象。全部患者家属均了解本次研究内容，自愿入组并签署知情同意书。研究获得医院伦理委员会批准，并上报相关部门备案。……