刘玉庆 许岩

[摘要] 目的 研究厄贝沙坦联合氨氯地平治疗2型糖尿病合并高血压的临床疗效。方法 随机选取2018年6月—2019年8月期间于该院收治的78例2型糖尿病合并高血压疾病患者开展临床研究，将其均分为普通组和联合组，每组39例。普通组患者仅使用厄贝沙坦药物治疗，联合组患者接受厄贝沙坦联合氨氯地平治疗，研究比较两组患者临床疗效。结果 联合组患者血糖控制效果优于普通组患者，组间差异有统计学意义（P<0.05）;联合组患者血压控制效果优于普通组患者，组间差异有统计学意义（P<0.05）;联合组患者治疗总有效率，较普通组患者高，组间差异有统计学意义（P<0.05）。 结论 厄贝沙坦联合氨氯地平在治疗2型糖尿病合并高血压方面的临床疗效较好，较单独使用厄贝沙坦临床疗效更好。

[关键词] 厄贝沙坦;氨氯地平;2型糖尿病;高血压;临床疗效

[中图分类号] R587.1          [文献标识码] A          [文章编号] 1672-4062（2020）05（b）-0006-03

Clinical Study of Irbesartan and Amlodipine in the Treatment of Type 2 Diabetes with Hypertension

LIU Yu-qing， XU Yan

Rizhao People's Hospital， Rizhao， Shandong Province， 276800 China

[Abstract] Objective To study the clinical efficacy of irbesartan combined with amlodipine in the treatment of type 2 diabetes with hypertension. Methods Randomly selected 78 patients with type 2 diabetes and hypertension who were admitted to the hospital from June 2018 to August 2019 for clinical research. They were divided into ordinary group and combined group， 39 cases in each group. Patients in the general group were treated with irbesartan only， and patients in the combination group received irbesartan combined with amlodipine. The clinical efficacy of the two groups was compared. Results The blood glucose control effect of the combination group was better than that of the ordinary group， and the difference between the groups was statistically significant （P<0.05）. The blood pressure control effect of the combination group was better than that of the ordinary group， with statistically significant differences between the groups （P<0.05）; The total effective rate of treatment in the combined group was higher than that in the ordinary group， and the difference between the groups was statistically significant（P<0.05）. Conclusion Irbesartan combined with amlodipine has a better clinical effect in the treatment of type 2 diabetes with hypertension， and it has better clinical effect than irbesartan alone.

[Key words] Irbesartan; Amlodipine; Type 2 diabetes; Hypertension; Clinical efficacy

2型糖尿病屬于常用的糖尿病类型，I型糖尿病患者发病年龄多不超过20岁，发病与遗传密切相关。与I型糖尿病相比，2型糖尿病病情控制难度更低，只要采取科学的病情管理手段，血糖水平能够保持在一个平稳范围内[1]。2型糖尿病患者血糖水平控制不佳的情况下，随着病情的延长，会并发其他心血管疾病，高血压属于2型糖尿病常见的并发疾病，2型糖尿病并发高血压疾病的情况下，将会加剧病情管理难度，对于患者身体健康影响非常大[2]。该文旨在探究厄贝沙坦联合氨氯地平用于治疗2型糖尿病合并高血压疾病的临床疗效，随机选取2018年6月—2019年8月期间于该院收治的78例2型糖尿病合并高血压疾病患者开展临床研究，现报道如下。

1  资料与方法

1.1  一般资料

随机选取该院收治的78例2型糖尿病合并高血压疾病患者开展临床研究，将其均分为普通组和联合组，每组39例。……