C02点阵激光治疗皮肤创伤性瘢痕的临床应用及研究进展
2020-07-29管晓玉纪覃吴灿白南
管晓玉 纪覃 吴灿 白南
[摘要]皮肤瘢痕给瘢痕患者的身心带来了巨大的痛苦,但传统的治疗方法并不能达到令人非常满意的治疗效果。近年来,激光作为新型治疗方法逐渐应用于瘢痕治疗,特别是CO2点阵激光取得了可喜的治疗效果,在临床中的应用也越来越广泛。CO2点阵激光依据点阵光热作用理论而研发,临床效果显著,不良反应少,有望与传统及脂肪干细胞、富血小板血浆、A型肉毒毒素等新型瘢痕治疗方式联合应用,为不同类型、不同时期的瘢痕提供更加行之有效的治疗方案。
[关键词]创伤性瘢痕;CO2点阵激光;理论基础;临床应用;A型肉毒毒素;脂肪干细胞;富血小板血浆
[中图分类号]R619+.6 [文献标志码]A [文章编号]1008-6455(2020)07-0169-03
Abstract: The skin scar brings great pain to the body and mind of the patients with scar, but the satisfactory effect remains elusive under conventional treatment. During recent years, laser treatment has gained popularity as a novel method for skin scar, highlighting the classical CO2 2fractional laser which exhibits promising results in reducing scar and its application in clinical practice is more and more extensive. According to Fractional photothermolysis theory CO2 fractional laser is developed ,and it gains significant clinical effects and few adverse reactions.In order to provide more effective treatment schemes for different types and different periods of scar,CO2 fractional laser is expected to be combined with traditional or new scar treatment methods such as Fadipose derived stem cells, Platelet-rich plasma and Botulinum toxin type A.
Key words: traumatic scar; CO2 fractional laser; theoretical basis; clinical application; botulinum toxin type A; fadipose derived stem cells; platelet-rich plasma
隨着现代生活水平的提高,人们的求美意识也越来越强烈。由外伤、烧伤、手术等造成的皮肤创伤性瘢痕对患者的外观、功能、心理及社会生活等造成严重影响,严重者会导致患者抑郁甚至自杀等风险。瘢痕的传统治疗方法很多,包括外科手术、硅酮制剂、放射、冷冻、加压、瘢痕内注射皮质类固醇和5-氟尿嘧啶等,这些传统的治疗方法虽然有一定的临床效果,但都有其局限性,没有一种单一的治疗方法能达到非常满意的治疗效果。近年来,随着光电技术理论及临床实践的发展,激光已广泛应用于瘢痕治疗。CO2点阵激光是治疗瘢痕的经典激光,本文对其治疗瘢痕的理论基础、临床应用、治疗时机及相关研究进展综述如下。
1 C02点阵激光治……
