王红丽

【摘要】 目的：探究胎膜早破型先兆流产患者应用利托君治疗的临床效果及对保胎成功率的影响。方法：将2017年2月-2019年2月笔者所在医院收治的86例胎膜早破型先兆流产患者作为研究对象，采用随机数字表法将其平均分为两组，每组43例。对照组应用硫酸镁进行治疗，试验组应用利托君进行治疗。对比两组治疗效果。结果：试验组保胎成功率显著高于对照组，差异有统计学意义（P<0.05）。试验组患者宫缩消失时间、孕龄延长时间均显著优于对照组，差异有统计学意义（P<0.05）。结论：采用利托君对胎膜早破型先兆流产患者进行治疗，能够提升保胎成功率，缩短患者宫缩消失时间，延长孕龄。

【关键词】 胎膜早破型; 先兆流产; 利托君; 保胎成功率

doi：10.14033/j.cnki.cfmr.2019.22.016 文献标识码 B 文章编号 1674-6805（2019）22-00-03

【Abstract】 Objective：To explore the clinical effect of Ritodrine treatment on the success rate of premature rupture of membranes with threatened abortion.Method：A total of 86 cases of threatened abortion with premature rupture of membranes admitted to our hospital from February 2017 to February 2019 were selected as the research objects，and they were divided into two groups by random number table method on average，with 43 cases in each group.The control group was treated with Magnesium Sulfate，while the experimental group was treated with Ritodrine.The therapeutic effects of the two groups were compared.Result：The success rate of fetal protection in the experimental group was significantly higher than that in the control group，and the difference was statistically significant（P<0.05）.The time of uterine contraction disappearance and gestational age prolongation in the experimental group were significantly better than those in the control group，the differences were statistically significant（P<0.05）.Conclusion：Using Ritodrine to treat threatened threatened abortion with premature rupture of membranes can improve the success rate of fetal preservation，shorten the time of disappearance of contractions，and prolong the gestational age.

【Key words】 Premature rupture of membranes; Threatened abortion; Ritodrine; Success rate of fetal protection

First-authors address：Peoples Hospital of Songzi City，Songzi 434200，China

所謂先兆流产，指的是产妇在妊娠28周之前，阴道内出现少量出血，患者会出现继发性的下腹部疼痛和腰部疼痛，对患者的盆腔进行检查，患者宫口并未完全打开，且阴道内无妊娠物流出，患者的子宫大小与孕周情况相符，若未及时采取措施进行干预，则会导致难免流产情况的出现，先兆流产患者大都会出现月经停止、阴道出血和腹部疼痛的病症[1]。据研究，其患病因素大多与胎膜早破相关，胎膜早破型先兆流产患者，由于在生产前出现胎膜自然破裂现象，其主要与创伤、宫颈内口松弛、感染、羊膜腔内压力升高等多种因素相关[2]，胎膜早破型先兆流产患者及胎儿的生命健康均会受到严重不良影响[3]。所以必须及时采取措施进行治疗干预，本研究就胎膜早破型先兆流产患者应用利托君治疗的临床效果及保胎成功率的影响进行分析，现报道如下。

1 资料与方法

1.1 一般资料

将2017年2月-2019年2月笔者所在医院收治的86例胎膜早破型先兆流产患者作为研究对象，纳入标准：两组患者均经临床诊断确诊为胎膜早破型先兆流产的患者;年龄均在18岁以上[4]。排除标准：严重心脑血管疾病的患者，肾脏功能衰竭的患者，多胎妊娠的患者，合并其他严重产科疾病的患者[5]。采用随机数字表法将其平均分为两组，每组43例。试验组患者年龄20～41岁，平均（29.63±2.11）岁;孕周20～28周，平均（23.23±1.45）周。对照组患者年龄21～42岁，平均（29.33±2.09）岁;孕周21～28周，平均（23.61±1.25）周。两组患者一般资料比较，差异无统计学意义（P>0.05），有可比性。