王娟

【摘 要】目的：探讨宫颈癌筛查中高危型HPV筛查与TCT、阴道镜联合检查的应用价值。方法：从2014年2月至2017年12月收治的宫颈癌筛查疑似为宫颈癌患者中挑选100例作为本次研究工作对象，均知情同意，签署《知情同意书》，并配合完成本次研究工作。所有对象均行高危型HPV筛查、TCT检查及阴道镜检查，并将单独TCT检查结果（对照组，n=100）和高危型HPV筛查与TCT、阴道镜联合检查（研究组，n=100）结果作比较分析。结果：研究组宫颈癌前病变检查有21例，宫颈癌检出有7例，合计28例，检出率为28.00%（28/100），对照组宫颈癌前病变检查有7例，宫颈癌检出有4例，合计11例，检出率为11.00%（11/100）;两组检出率比较，研究组检出率显著高于对照组，χ2=9.2053，P=0.0024。结论：应用高危型HPV筛查与TCT、阴道镜联合检查可以明显提高宫颈癌筛查检出率。

【关键词】宫颈癌筛查;高危型HPV筛查;TCT;阴道镜;检查

Application of high-risk HPV screening and combined examination of TCT and colposcopy in cervical cancer screening

Wang Juan

Wenchuan County People's Hospital， Abei， Sichuan 623000

[Abstract] Objective：To investigate the application of high-risk HPV screening and TCT and colposcopy in cervical cancer screening. Methods：The cervical cancer screening from February 2014 to December 2017 was selected. 100 patients suspected to be cervical cancer were selected as the subjects of this study. They all informed consent and signed the “informed consent form”. All subjects were high-risk HPV screening， TCT examination and colposcopy. The results of TCT examination （control group， n=100） and high-risk HPV screening were compared with TCT and colposcopy. Results：There were 21 cases of cervical precancerous lesions in the study group， 7 cases of cervical cancer detected， 28 cases in total， the detection rate was 28.00% （28/100）， and 7 cases of cervical precancerous lesions in the control group， cervical cancer examination. There were 4 cases， a total of 11 cases， the detection rate was 11.00% （11/100）; the detection rate of the two groups was significantly higher than that of the control group， 2 values χ2= 9.2053，P value=0.0024. Conclusion：The application of high-risk HPV screening combined with TCT and colposcopy can significantly improve the screening rate of cervical cancer screening.

[Key words]Cervical cancer screening; High-risk HPV screening; TCT; Colposcopy; Examination

宫颈癌为临床常见的恶性肿瘤疾病之一，好发于女性人群，其發病率仅次于乳腺癌，因此具有较高的疾病发生率。随着社会发展进步，生活水平提高，生活压力、工作压力等加重，宫颈癌发生率呈持续性上升发展趋势，对患者的身体健康、生命健康均造成极大影响。通过早期诊断、早期治疗，可以有助于预防发生癌变恶化，更是目前临床的治疗关键[1-2]。本次研究工作旨在探讨宫颈癌筛查中高危型HPV筛查与TCT、阴道镜联合检查的应用价值。现报道如下。

1 资料与方法

1.1 一般资料

从2014年2月至2017年12月收治的宫颈癌筛查疑似宫颈癌患者中挑选100例作为本次研究工作对象，均知情同意，签署《知情同意书》，并配合完成本次研究工作。……