胃肠道间质肿瘤的影像学表现与病理对照研究(附18例临床分析)
2019-10-21石德强许晓清祁波王翠娇
石德强 许晓清 祁波 王翠娇
【摘 要】目的:通过分析胃肠道间质瘤的影像学征象并与手术病理对照研究,以提高影像学诊断水平。 方法:搜集经手术病理证实的18例GIST的病例资料,均行胃肠道钡餐造影,其中10例术前CT检查,对其影像学表现及病理对照研究进行回顾性分析。结果:病灶分布于胃10(10/18)例、小肠5(5/18)例、食管1(1/18)例、直肠1(1/18)例、胃肠外1(1/18)例。主要影像学表现为粘膜下富血供肿块,境界清晰光整,外生性为主,内部出血、坏死、囊变明显。肿块呈圆形或类圆形,一侧肠壁粘膜局限性消失破坏,有时可见偏侧性龛影,恶性间质瘤表现为不规则分叶状肿块,凹凸不平龛影,局部淋巴结无转移。病理分型:粘膜下型2例,占11.1%;肌壁间型12例,占66.7%;浆膜下型3例,占16.7%;胃肠外型1例,占5.5%。结论:GIST影像学表现具有一定特征,对诊断有一定价值,但缺乏特异性,定性困难,要明确诊断需依靠病理及免疫组织化学检查。
【关键词】胃肠道;间质瘤;临床病理;X线;X线计算机;体层摄影
【中图分类号】R735 【文献标识码】A 【文章编号】1004-7484(2019)01-0012-02
Gastrointestinal stromal tumors imaging findings and pathology study (clinical analysis of 18 cases)
SHI De-qiang, QI Bo, XU Xiao-qing, WANG Cui-jiao
Department Of Radiology, Shan Dong Qing Dao,The Centre Hospital Of Jiao Zhou ,Qing Dao,Jiao Zhou 266300 China
【Abstract】Objective: Through the analysis of gastrointestinal stromal tumor imaging findings andpathology and operation research,in order to improve the level of imaging diagnosis. Methods: Confirmed by operation and pathology in 18 cases were GIST records, underwent gastrointestinal barium meal, including 10 cases of preoperative CT examination, the imaging manifestations and pathology were retrospectively analyzed. Results: Distribution of lesions in 10 cases of gastric,Small intestine in 5 cases, 1 cases of esophagus, rectum in 1 cases, 1 cases of gastrointestinal tract. The main imaging findings of submucous hypervascular masses, the boundary clear finishing, external, internal bleeding, necrosis,cystic change obviously, the mass is round or oval, side of the intestinal wall and mucosa damage limitation disappears, sometimes visible laterality niche, malignant stromal tumor showed irregular lobulated mass, uneven crater, local lymph node metastasis. Pathological typing: Submucosal type in 2 cases, accounting for 11.1%; intramural type in 12 cases, accounting for 66.7%; the subserosal type in 3 cases, accounting for 16.7%; parenteral type in 1 cases, accounting for 5.5%. Conclusion: Imaging findings of GIST has certain characteristics, the diagnosis, but lack of specificity, qualitative hard, to confirm the diagnosis depends on pathologic and immunohistochemical examinations.
【Key words】Gastrointestinal tract; Stromal tumor; Clinical pathology; X ray; X ray computed; Tomography;
胃腸道间质肿瘤(gastrointestinal stromal tumor,GIST),是一种来源于胃肠道壁内的Cajal间质细胞的肿瘤,目前认为它是一类既不同于典型平滑肌瘤,亦不同于雪旺细胞瘤的胃肠道最常见的间叶源性肿瘤〔1〕。Mazur等〔2〕在1983年发现部分胃肠非上皮梭形细胞肿瘤,具有不完全分化特点,首先提出“胃肠间质瘤”。以往文献以病理研究或个案报道居多,有关GIST钡餐造影和CT表现的详细报道很少〔3-5〕。我院1990年1月—2016年8月对18例GIST患者的临床影像学及手术病理资料进行如下分析研究:……p>
