邬素珍 许焕英 陈玉

摘要：目的  探索子宮内膜异位症（EM）痛经患者体质分布规律。方法  采用王琦教授的《中医体质量表》，对2016年1月～2019年1月我院200例EM痛经患者（病例组）和200例健康女性（对照组）进行体质研究，并根据中华中医药学会发布的《中医体质分类与判定标准》进行体质分类及判定。结果  两组间平和质、阳虚质、血瘀质、气郁质比较，差异均有统计学意义（P<0.05）。重度EM痛经患者中血瘀质分布较轻度EM痛经患者、中度EM痛经患者占比大，差异有统计学意义（P<0.05），轻度EM痛经患者中血瘀质分布与中度EM痛经患者相当，差异无统计学意义（P>0.05）。CA125≥100 U/L患者的血瘀质分布较CA125正常患者、35 U/L≤CA125<100 U/L患者占比大，差异有统计学意义（P<0.05），CA125正常患者的血瘀质分布与35 U/L≤CA125<100 U/L患者相当，差异无统计学意义（P>0.05）。结论  EM痛经患者与健康女性的体质分布上存在有明显不同，以阳虚质、血瘀质、气郁质为主。EM痛经程度、血清CA125水平与血瘀质分布具有相关性，重度EM痛经患者和血清CA125水平≥100 U/L患者，血瘀质分布的占比大。

关键词：子宫内膜异位症;痛经;体质分布;血瘀质

中图分类号：R271.9                                 文献标识码：A                                 DOI：10.3969/j.issn.1006-1959.2019.15.025

文章编号：1006-1959（2019）15-0080-04

Abstract：Objective  To explore the distribution of body constitution in patients with endometriosis （EM） dysmenorrhea.Methods  Using Professor Wang Qi's "Traditional Chinese Medicine Quality Table"， 200 patients with EM dysmenorrhea （case group） and 200 healthy women （control group） were enrolled in our hospital from January 2016 to January 2019， and according to Chinese The classification and judgment criteria for TCM constitution and quality issued by the Chinese Medicine Association are classified and judged. Results  There were significant differences in the quality of Pinghe， Yang deficiency， blood stasis and qi stagnation between the two groups （P<0.05）. The distribution of blood sputum in patients with severe EM dysmenorrhea was higher than that in mild EM dysmenorrhea group and moderate EM dysmenorrhea group， the difference was statistically significant （P<0.05）. The distribution and moderate sputum in patients with mild EM dysmenorrhea group Patients in the EM dysmenorrhea group were comparable，the difference was not statistically significant （P>0.05）. The distribution of blood stasis in CA125≥100 U/L group was larger than that in CA125 normal group， 35 U/L≤CA125<100 U/L group， the difference was statistically significant （P<0.05）， CA125 normal group the blood sputum distribution of patients was similar to that of 35 U/L ≤ CA125<100 U/L group， the difference was not statistically significant （P>0.05）. Conclusion  There is a significant difference in the distribution of EM dysmenorrhea and healthy women. The yang deficiency， blood stasis and qi stagnation are the main factors. The degree of EM dysmenorrhea， serum CA125 level and blood sputum distribution were correlated. Patients with severe EM dysmenorrhea and serum CA125 level ≥100 U/L had a large proportion of blood sputum distribution.

Key words：Endometriosis;Dysmenorrhea;Constitutional distribution;Bloody sputum

子宫内膜异位症（Endometriosis，EM）是指具有生长功能的子宫内膜组织出现在子宫体以外的部位而引起的疾病，多发于育龄期妇女，病变部位多发生在盆腔脏器，具有增生、浸润、转移及复发等恶性行为，可形成结节及包块，引起疼痛和不孕等，是目前最为常见的妇科疑难病[1]。EM以继发性痛经和进行性加重，痛经的反复发作为典型表现，对患者的身心健康及生活质量造成了严重影响[2]。目前EM痛经的发病机制尚不明确，西医治疗多用激素治疗或手术治疗，但用药期间的类更年期症状等副作用大、价格昂贵，除根治手术外复发率高[3]。中医认为疾病的发生与人体体质有明显的相关性，因此探讨EM痛经患者的体质分布规律，从而对该病进行有效的治疗和预防，意义深远。……