林德华

【摘要】 目的：探讨使用BIPAP呼吸机设备治疗睡眠呼吸暂停（OSAS）并肺心病呼吸衰竭（COPD）的临床效果。方法：从笔者所在医院呼吸科2016年1月-2018年9月收治的患者中抽取120例进行观察，分别抽取60例采用常规治疗和60例采取BIPAP呼吸機治疗，设置对照组与试验组，采用回顾性分析法，比较两组最长呼吸暂停时间、最低通气时间、呼吸紊乱指数、最高和最低动脉血氧饱和度（SaO2），对比治疗前后患者氧分压（PaO2）、二氧化碳分压（PaCO2）、经皮血氧饱和度（SpO2）等血气分析指标，统计两组治疗满意度并进行比较。结果：治疗前两组呼吸参数比较差异无统计学意义（P>0.05），治疗后两组各项指标均优于治疗前，且试验组均优于对照组，差异均有统计学意义（P<0.05）。治疗前两组血气指标比较差异无统计学意义（P>0.05），治疗后两组指标均优于治疗前，且试验组均优于对照组，差异均有统计学意义（P<0.05）。试验组治疗总满意度为90.7%（55/60），对照组总满意率为71.7%（43/50），试验组高于对照组，差异有统计学意义（字2=8.015，P<0.05）。结论：采用BIPAP呼吸机治疗OSAS并COPD患者，可有效改善患者的呼吸参数和血气状况，缓解患者病情和呼吸状况，相较于传统的常规治疗方式，治疗效果更加明显，利于提升患者满意度。

【关键词】 BIPAP呼吸机; 睡眠呼吸暂停; 肺心病呼吸衰竭

doi：10.14033/j.cnki.cfmr.2019.27.066 文献标识码 B 文章编号 1674-6805（2019）27-0-03

BIPAP Ventilator in Treatment of Sleep Apnea Complicated with Respiratory Failure of Cor Pulmonale/LIN Dehua.//Chinese and Foreign Medical Research，2019，17（27）：-155

【Abstract】 Objective：To explore the therapeutic measures and effects of BIPAP ventilator on patients with sleep apnea（OSAS） and pulmonary heart disease and respiratory failure（COPD）.Method：A total of 120 patients were selected from hospital respiratory department from January 2016 to September 2018 for observation.A totaol of 60 patients were treated with conventional therapy and 60 patients were treated with BIPAP ventilator.The control group and the experimental group were set up.The longest apnea time and the lowest ventilation of the two groups were compared by retrospective analysis.Time，respiratory disorder index，maximum and minimum arterial oxygen saturation（SaO2） were compared before and after treatment.Blood gas analysis indexes such as partial pressure of oxygen（PaO2），partial pressure of carbon dioxide （PaCO2） and percutaneous oxygen saturation（SpO2） were compared between the two groups.Result：There was no significant difference in respiratory parameters between the two groups before treatment（P>0.05）.After treatment，the indexes of the two groups were better than those before treatment，and the experimental group was superior to the control group，the difference was statistically significant（P<0.05）.There was no significant difference in blood gas indexes between the two groups before treatment（P>0.05）.After treatment，the indexes of the two groups were better than those before treatment，and the experimental group was superior to the control group，the difference was statistically significant（P<0.05）.The total satisfaction rate of the experimental group was 90.7%（55/60），and that of the control group was 71.7%（43/50），the difference between the experimental group and the control group was statistically significant （字2=8.015，P<0.05）.Conclusion：BIPAP ventilator can effectively improve the respiratory parameters and blood gas status of patients with OSAS and COPD，alleviate the patients condition and respiratory status.Compared with the traditional conventional treatment，BIPAP ventilator has more obvious therapeutic effect，which is conducive to improving the patients satisfaction with the treatment.

【Key words】 BIPAP ventilator; Sleep apnea; Respiratory failure of cor pulmonale

First-authors address：Lianjiang County Hospital，Lianjiang 350500，China

睡眠呼吸暫停（阻塞性睡眠呼吸暂停综合征，OSAS）与肺心病呼吸衰竭（慢性塞性肺疾病，COPD）均属于常见临床呼吸疾病，且两者常以合并形式存在，合并后也被称为“重叠综合征”，该类患者病发后，受与睡眠有关的低氧血症与肺动脉高压影响，容易导致慢性肺心病，引发呼吸衰竭，甚至危及患者的生命安全[1-2]。对此有效治疗措施的应用至关重要，而本次研究重点探讨BIPAP呼吸机的应用方式和效果，具体报道如下。

1 资料与方法

1.1 一般资料

将笔者所在医院2016年1月-2018年9月收治的120例OSAS合并COPD患者作为研究对象。纳入标准：（1）全部患者经诊断均患有OSAS合并COPD症状;（2）动脉血气分析为PaO2<

60 mm Hg、PaCO2>55 mm Hg。排除标……