刘淼

【摘要】 目的：探討依托咪酯复合丙泊酚对无痛人工流产苏醒后情绪的影响。方法：选择笔者所在医院接受的160例无痛人流患者，将其随机分为对照组及观察组，每组80例。对照组术中给予丙泊酚麻醉，观察组给予依托咪酯联合丙泊酚麻醉。观察比较两组患者麻醉起效时间、苏醒时间、麻醉效果、麻醉不良反应发生情况及情绪评分。结果：两组麻醉起效时间比较差异无统计学意义（P>0.05）。观察组苏醒时间长于对照组，差异有统计学意义（P<0.05）。两组患者麻醉优良率比较差异无统计学意义（P>0.05）。观察组麻醉不良反应发生率低于对照组，差异有统计学意义（P<0.05）。术后两组患者正性情绪评分均较术前提高（P<0.05），且观察组高于对照组，差异有统计学意义（P<0.05）。术后两组患者负性情绪评分均较术前降低（P<0.05），且观察组低于对照组，差异有统计学意义（P<0.05）。结论：依托咪酯复合丙泊酚能够减少术后不良反应的发生，且对术后情绪恢复更为有利。

【关键词】 依托咪酯; 丙泊酚; 无痛人流; 情绪

doi：10.14033/j.cnki.cfmr.2019.27.024 文献标识码 B 文章编号 1674-6805（2019）27-00-03

Effects of Etomidate Combined with Propofol on Emotion after Recovery of Painless Artificial Abortion/LIU Miao.//Chinese and Foreign Medical Research，2019，17（27）：-57

【Abstract】 Objective：To investigate the effect of Etomidate combined with Propofol on emotion after recovery of painless artificial abortion.Method：A total of 160 cases of patients with painless artificial abortion in our hospital were selected and randomly divided into the control group and the observation group，with 80 cases in each group.The control group was given Propofol anesthesia during operation，while the observation group was given Etomidate combined with Propofol anesthesia.The anesthesia onset time，recovery time，anesthesia effect，adverse reactions and emotional scores were observed and compared between the two groups.Result：There was no significant difference in the onset time of anesthesia between the two groups（P>0.05）.The recovery time of the observation group was longer than that of the control group，the difference was statistically significant（P<0.05）.There was no statistically significant difference in the superior rate of anesthesia between the two groups（P>0.05）.The incidence of adverse reactions of anesthesia in the observation group was lower than that in the control group，the difference was statistically significant（P<0.05）.The positive emotional scores in the two groups were higher after operation than before operation（P<0.05），and the observation group was higher than the control group，the difference was statistically significant（P<0.05）.The negative emotional scores in the two groups were lower after operation than before operation（P<0.05），and the observation group was lower than the control group，the difference was statistically significant（P<0.05）.Conclusion：Etomidate combined with Propofol can reduce the incidence of adverse reactions after surgery，and is more beneficial for the recovery of emotion after operation.

【Key words】 Etomidate; Propofol; Painless abortion; Emotion

First-authors address：Peoples Hospital of Tonghua City，Tonghua 134001，China

无痛人流多采用短效镇静、镇痛药物，在保障手术需要的同时又能够快速复苏，但短效麻醉藥物作用迅速，麻醉过程中患者呼吸抑制、血流动力学不稳定等不良反应也较多[1]，另意外妊娠患者多存在不同程度的不良心理情绪[2]，而人流术中的麻醉药物对患者苏醒后的情绪产生一定影响，丙泊酚起效迅速，是无痛人流最常用的麻醉药物，依托咪酯也为短效镇静药物，近年来笔者所在医院在无痛人工流产中采用依托咪酯复合丙泊酚进行麻醉，具有较好的效果，现报告如下。

1 资料与方法

1.1 一般资料

选择笔者所在医院2018年6-12月接收的无痛人流患者160例，纳入标准：（1）妊娠经超声及血清学检查诊断明确;（2）超声提示宫内妊娠;（3）妊娠<12周。排除标准：（1）合并生殖道畸形或子宫手术史;（2）合并生殖道感染;（3）合并凝血宫内障碍;（4）合并其他器官系统严重疾病。将患者随机分为对照组及观察组，每组80例。对照组患者年龄22～36岁，平均（29.6±3.6）岁;

妊娠次数1～4次，平均（1.50±0.27）次;初产妇38例，经产妇42例;平均分娩次数（0.77±0.26）次;孕周6～10周，平均（9.5±1.3）周。观察……