俞舜

[摘要]目的：探讨微等离子体射频联合曲安奈德治疗增生性瘢痕的临床效果。方法：选取2015年11月-2017年10月在笔者医院接受治疗的80例增生性瘢痕患者。采用数字表法分组，将患者随机分为对照组和观察组，每组40例。对照组接受微等离子体射频技术治疗，完成后再接受超声导入氯化钠注射液治疗;观察组患者微等离子体射频技术治疗后，再接受超声导入曲安奈德注射液治疗。使用温哥华瘢痕评分量化表（VSS）对两组患者的瘢痕治疗情况进行评估，同时对比两组患者干预前后的焦虑、抑郁及主观幸福感。结果：两组患者治疗后VSS评分均显著降低，其差异具有统计学意义（P<0.05），治疗后观察组患者VSS评分显著低于对照组（P<0.05）。治疗前两组患者的焦虑抑郁症状分数以及主观幸福感差异无统计学意义（P>0.05），治疗后观察组的焦虑抑郁症状评分均显著低于对照组（P<0.05），主观幸福感显著高于对照组（P<0.05）。结论：临床上针对增生性瘢痕患者采取微等离子体射频联合曲安奈德超声导入治疗的方式能够起到良好的效果，治疗后症状均能够显著消退，且无不良反应，患者的不良情绪可获得显著缓解，提升幸福感。

[關键词]曲安奈德;超声导入;微等离子体射频;增生性瘢痕;焦虑;抑郁

[中图分类号]R619+.6    [文献标志码]A    [文章编号]1008-6455（2019）02-0063-03

Abstract：  Objective  To study the clinical effect of microplasma radiofrequency and triamcinolone acetonide in hypertrophic scar patients. Methods  Patients with hypertrophic scar treated in our hospital were selected from November 2015 to October 2017 with 80 cases. According to the design and numerical method， the patients were divided into two groups： control group （40 cases） and observation group （40 cases）. The control group was treated with microplasma radiofrequency technique， and then treated with ultrasonic iontophoresis sodium chloride injection， while the patients in the observation group were treated with microplasma radiofrequency technique. Then the ultrasonic instrument was used to treat triamcinolone acetonide injection. Treatment of scar in two groups using Vancouver scar scale and VSSs At the same time， anxiety， depression and subjective well-being were compared before and after intervention. Results  The VSS score of the two groups was significantly lower than that of the control group （P<0.05），and the VSS score of the observation group was significantly lower than that of the control group （P<0.05）.There was no significant difference in the scores of anxiety and depression symptoms and subjective well-being between the two groups before treatment （P>0.05）， but the scores of anxiety and depression symptoms in the observation group were significantly lower than those in the control group （P<0.05）， and the subjective well-being was significantly higher than that in the control group （P<0.05）.Conclusion The combination of microplasma radiofrequency （RF） and triamcinolone acetonide （triamcinolone acetonide） was used to treat hypertrophic scar patients. The patient's bad mood can obtain the remarkable relief，enhances the happiness.

Key words： triamcinolone acetonide; ultrasound introduction; microplasma radiofrequency; hypertrophic scar;anxiety;depression

增生性瘢痕主要是创面在愈合中发生失控后的病理产物，主要由胶原等细胞间质过度沉积产生[1]。因有碍美观且严重，亦可影响机体的活动功能，所以临床上一直在不断追寻安全且有效的治疗办法。近年来的研究表明，结合手术切除、药物和激光治疗等方法，能够达到取长补短的效果，具有良好的疗效，也能减少一定的不良反应[2-3]。目前，应用手术、单纯激素注射等治疗方法尽管疗效显著，但会有二次损伤和组织萎缩等问题[4]。微等离子体射频技术是瘢痕治疗的前沿技术，具有良好效果且不良反应低，因而在临床上的应用较为广泛[5]。……