激光治疗婴幼儿浅表性血管瘤的疗效及并发症分析
2019-03-13汪城河苏晓灵苏振民林文雄吴雅莹蔡加滨林东福
汪城河 苏晓灵 苏振民 林文雄 吴雅莹 蔡加滨 林东福
[摘要]目的:探讨595nm PDL/1 064nm Nd∶YAG激光治疗婴幼儿血管瘤的疗效及并发症,评估其安全性及治疗效果。方法:回顾性分析2014年1月-2016年12月笔者科室收治的接受激光治疗的828例婴幼儿血管瘤患者病例资料,统计其疗效及并发症发生情况。结果:828例婴幼儿血管瘤(年龄≤6个月)接受激光治疗,单项并发症发生情况:水疱103例(12.44%)、色素脱失54例(6.52%)、色素沉着12例(1.45%)、浅表瘢痕27例(3.26%)、溃疡24例(2.90%),复发7例(0.85%),有43例(5.19%)因效果不佳改用其他治疗方案,总有效率82.49%、优良率76.21%。结论:595nm PDL/1 064nm Nd∶YAG激光治疗婴幼儿浅表性血管瘤安全性较高,副作用小。
[关键词]血管瘤;PDL;Nd:YAG激光;婴幼儿;浅表性;并发症
[中图分类号]R732.2 [文献标志码]A [文章编号]1008-6455(2019)02-0056-04
Abstract: Objective To analysis of complication of laser treatment for infantile hemangioma, therapeutic safety and significance. Methods Laser was applied to 828 cases with infantile hemangiomas (IH) in Quanzhou Children Hospital,Department of Plastic Surgery from January 2014 to December 2016. Results 828 cases(≤ 6 months)of IH conforms to the standard,the total effective rate was 82.49% (683 cases), in the meantime the excellent and good rate was 76.21% (520 cases).The single side effect included blisters (103 cases,12.44%),hypopigmentation (54 cases,6.52%),hyperpigmentation (12 cases,1.45%),superficial scar (27 cases,3.26%).ulceration (24 cases,2.9%),relapse (7cases,0.85%).At the same time,because of the treatment effect were not ideal,43 cases were switched to other therapies. Conclusion The 595nm pulsed dye laser and 1 064nm Nd:YAG lager is an effective treatment for superficial hemangioma of infants with high security and few side reactions.
Key word: hemangioma; pulsed dye laser;Nd:YAG laser;superficial;infantile; complication
婴幼儿血管瘤(infantile hemangiomas,IH)是婴幼儿常见的良性肿瘤,主要发生于1岁以内的婴幼儿[1],发病率高达l%~10%,女性发病率较高,好发于头颈部。IH的临床治疗,根据瘤体的分期、患儿年龄、部位及大小等应区别对待。因此,本文回顾性分析2014年1月-2016年12月笔者科室采用595nmPDL/1 064nm Nd:YAG激光治疗的婴幼儿血管瘤病例资料,探讨激光在IH治疗中的疗效及并发症情况,现报道如下。
1 资料和方法
1.1 一般资料: 研究对象为2014年1月-2016年12月在笔者科室接受激光治疗的1 179例婴幼儿血管瘤病例,筛除未随访的154例、年龄超过6个月的197例,共有828例患儿被纳入研究对象,其中男354例,女474例,年龄0.3~6个月,平均(2.86±1.51)个月。瘤体直径最大8cm,最小0.1cm,平均(1.76±1.18)cm。瘤体部位:面颈部270例,躯干248例,四肢210例,头皮100例,其中82例为多发性血管瘤(>3个瘤体),并发溃疡者14例。
1.2 纳入及排除标准:纳入标准:①依据国际脉管协会(ISSVA)制定的诊断分类标准,根据病史、临床表现,结合彩超或MRI检查明确诊断为血管瘤;②年龄小于6个月的增生期患儿,未经任何治疗且瘤体深度不超过0.5cm。……
