埃索美拉唑肠溶片联合莫沙必利治疗反流性食管炎的疗效及生活质量的临床研究
2019-01-13林进乾林龙根
林进乾 林龙根
[摘要] 目的 研究埃索美拉唑肠溶片联合莫沙必利治疗反流性食管炎的疗效及生活质量的影响。 方法 方便选取该院2015年5月—2018年4月接收的反流性食管炎患者90例,平均分为两组,对照组45例,使用莫沙必利治疗,观察组45例,使用埃索美拉唑肠溶片联合莫沙必利治疗。 结果 观察组治疗有效率为95.56%,明显高于对照组治疗有效率80.00%,差异有统计学意义(χ2=4.580,P<0.05)。 结论 在对反流性食管炎患者进行治疗时,使用埃索美拉唑肠溶片联合莫沙必利能够取得更好的治疗效果,患者的临床症状能够得到快速改善,生活质量能够得到显著提升,治疗有效率也非常高,具有较高的临床应用价值。
[关键词] 埃索美拉唑肠溶片;莫沙必利;反流性食管炎;疗效;生活质量
[中图分类号] R571 [文献标识码] A [文章编号] 1674-0742(2019)11(a)-0096-03
Clinical Study on the Efficacy and Quality of Life of Esomeprazole Enteric-coated Tablets Combined with Mosapride in the Treatment of Reflux Esophagitis
LIN Jin-qian, LIN Long-gen
Emergency Department, Sanming First Hospital Affiliated to Fujian Medical University, Sanming, Fujian Province, 365000 China
[Abstract] Objective To study the efficacy and quality of life of esomeprazole enteric-coated tablets combined with mosapride in the treatment of reflux esophagitis. Methods 90 patients with reflux esophagitis received from May 2015 to April 2018 in the hospital were Convenient selected and divided into two groups. The control group consisted of 45 patients, treated with mosapride, and 45 patients in the observation group used sommerzol enteric-coated tablets combined with mosapride. Results The effective rate of the observation group was 95.56%, which was significantly higher than that of the control group (80.00%). The difference was statistically significant (χ2=4.580, P<0.05). Conclusion In the treatment of patients with reflux esophagitis, the use of esomeprazole enteric-coated tablets combined with mosapride can achieve better therapeutic results, the clinical symptoms of patients can be improved quickly, and the quality of life can be significantly improved. The treatment efficiency is also very high, with high clinical application value.
[Key words] Esomeprazole enteric-coated tablets; Mosapride; Reflux esophagitis; Efficacy; Quality of life
反流性食管炎是臨床上较为常见的疾病类型,在中老年人群、精神压力较大的人群、吸烟人群、饮酒人群以及肥胖人群中的发病率都非常高,主要是由胃和十二指肠的内容物反流所导致的,主要是由各种因素导致的上消化道运动障碍性疾病,患者的胆汁酸、胰酶、胃酸等液体经患者的食道反流,如不及时治疗,可能会导致患者出现食管黏膜糜烂、食管出现溃疡或者纤维化,并发各种炎症等,对患者的身体健康和生活质量会造成不良影响[1]。临床上经常使用抑酸剂和促胃动力药物对反流性食管炎患者进行治疗,为了研究埃索美拉唑肠溶片联合莫沙必利治疗反流性食管炎的疗效及生活质量的影响,方便选取该院2015年5月—2018年4月接收的反流性食管炎患者90例,平均分为两组,分别使用莫沙必利和埃索美拉唑肠溶片联合莫沙必利治疗,现报道如下。
1 资料与方法
1.1 一般资料
方便选取该院……
