针刺复合静脉麻醉用于甲状腺良性结节消融术的临床观察
2018-10-21杨晓英沈韩雄马思杰严赟陈海虹沈睿王小平
杨晓英 沈韩雄 马思杰 严赟 陈海虹 沈睿 王小平
摘要 目的:评价针刺复合静脉麻醉用于甲状腺良性结节微波消融手术的临床效果。方法:选取2016年10月至2018年2月在上海中医药大学附属市中医医院接受甲状腺良性结节微波消融手术的患者66例,随机分为观察组和对照组,每组33例,观察组采用针刺复合静脉麻醉,对照组采用常规静脉麻醉的方法,观察2组镇痛镇静效果、静脉麻醉药的用量、术中打鼾和呼吸抑制发生率以及麻醉前、术毕、术后第1天血清皮质醇(Cor)含量的变化。结果:2组均取得了良好的镇痛和镇静效果;在观察组不用异丙酚的情况下,右美托咪定和芬太尼的用量与对照组比较,差异无统计学意义(P>0.05);观察组术中打鼾和呼吸抑制发生率明显低于对照组;血清Cor含量的变化组间比较,差异无统计学意义(P>0.05),组内比较,2组麻醉前和术毕血清Cor含量差异均无统计学意义(P>0.05),术后第1天早上血清Cor含量较麻醉前和术毕均明显下降,差异有统计学意义(P<0.05)。結论:针刺复合静脉麻醉用于甲状腺良性结节微波消融手术镇痛镇静效果良好,能够减少静脉麻醉药用量;降低术中打鼾和呼吸抑制的发生率,并可以降低术后应激反应。
关键词 针刺复合麻醉;微波消融术;镇痛;镇静;血清皮质醇;甲状腺;良性结节;消融术
AbstractObjective:Toinvestigatetheeffectofacupuncturecombinedintravenousanesthesiainmicrowaveablationofbenignthyroidnodules.Methods:Atotalof66patientsinourhospitalfromOctober2016toFebruary2018whoconformedtotheinclusioncriteriaandreceivedmicrowaveablationweredividedintotwogroupsrandomly.Acupuncturecombinedintravenousanesthesia(Treatmentgroup,33cases)andconventionalintravenousanesthesiaalone(Controlgroup,33cases)wereperformed.Theanalgesiceffect,sedativeeffect,anestheticdosage,incidencerateofsnoringandrespiratorydepression,andserumcortisollevelbeforeandafteroperationwereexaminedintwogroups.Results:Bothtwogroupsobtainedsatisfactoryanestheticeffect.Therewerenosignificantdifferenceinthedosesofdexmedetomidineandfentanylbetweentwogroups,butthetreatmentgroupdidnotusepropofol.Comparedwithcontrolgroup,patientsintreatmentgrouphadlowerincidencerateofsnoringandrespiratorydepression.Intermsofcortisollevel,therewerenosignificantdifferencesbetweentwogroups.Cortisollevelinthefirstdayaftersurgerywaslowerthanthatbeforeandafteroperation.Conclusion:Acupuncturecombinedwithintravenousanesthesiahassatisfactoryanesthesiaeffectinmicrowaveablationofbenignthyroidnodules.Itcanobviouslydecreasethedosageofnarcotic,adverseeffectsrate,andpostoperativestressresponse.
KeyWordsAcupuncturecombinedintravenousanesthesia;Thyroidnodule;Microwaveablation;Analgesiceffect;Sedativeeffect;Serumcortisol
中图分类号:R245.31+1文献标识码:Adoi:10.3969/j.issn.1673-7202.2018.06.055
针刺麻醉作为一种辅助手段,被广泛应用于传统的甲状腺手术中[1]。近年来,甲状腺良性结节微波消融手术成为治疗甲状腺良性病变的主要方法之一[2-3],我们将针刺复合静脉麻醉用于甲状腺良性结节微波消融术,观察针刺复合静脉麻醉用于甲状腺良性结节微波消融术的镇静镇痛效果,术中不良反应、以及对手术前后血清皮质醇(Cor)含量的影响,以评价针刺复合静脉麻醉用于甲状腺良性结节消融术的临床效果。……p>
