加味补阳还五汤联合西药对脑梗死患者临床疗效
2018-10-21魏青
魏青
摘要 目的:探讨加味补阳还五汤联合西药对脑梗死患者临床疗效、血脂以及血液流变学产生的影响。方法:选取2015年2月至2017年5月在北京中医医院顺义医院脑病科的脑梗死患者160例,采用随机数表法将患者分为对照组和观察组,每组80例。其中对照组采用常规西药进行治疗,观察组则在对照组基础上给予加味补阳还五汤,采用神经功能缺损(NIHSS)和日常生活能力(Barthel)指数分别对其治疗效果进行评分,根据所得数据分析血脂、血液流变学的变化。结果:2组患者治疗前NIHSS及Barthel指数评分差异无统计学意义(P>0.05),治疗后NIHSS评分均有所降低(P<0.05),但观察组分数明显大于对照组(P<0.05);治疗后Barthel指数评分均有所升高(P<0.05),但观察组升高程度明显大于对照组(P<0.05);2组患者在治疗前,NIHSS评分中意识、凝視、视野、面瘫、上下肢运动、语言等评分差异无统计学意义(P>0.05),治疗后2组患者各评分有所下降(P<0.05),但观察组各评分明显低于对照组,差异有统计学意义(P<0.05)。2组患者治疗前TC、TG、LDL-C水平差异无统计学意义(P>0.05),治疗后上述指标值均明显降低,且观察组降低的水平明显低于对照组(P<0.05);2组患者治疗前血液流变学水平差异无统计学意义(P>0.05),血液流变学指标数值在治疗后均有所降低,但观察组降低程度明显大于对照组,差异有统计学意义(P<0.05)。结论:加味补阳还五汤与西药联合治疗有利于改善脑梗死患者神经功能,提升其日常生活能力,同时降低患者的血脂并改善其血液流变学水平。
关键词 脑梗死;益气活血;补阳还五汤;西药;血脂;血液流变学
AbstractObjective:ToobservetheeffectofJiaweiBuyangHuanwudecoctioncombinedwithwesternmedicineontheclinicaleffect,bloodlipidandhemorheologyinpatientswithcerebralinfarction.Methods:Atotalof160casesofcerebralinfarctionadmittedtoourhospitalfromFebruary2015toMay2017wereselectedanddividedintocontrolgroupandobservationgroupaccordingtotherandomnumbertablemethod,80casesineachgroup.Thepatientsinthecontrolgroupusingconventionalwesternmedicinetreatment,theobservationgroupinthecontrolgroupweregivenflavoredYangalsofivesoup,thenervefunctiondefect(NIHSS)andtheabilityofdailylife(Barthel)assessedthetherapeuticeffectindexoftwogroupsofpatients,andtoanalyzethechangesofbloodlipidandHemorheologyinthetreatmentofemergence.Results:TwogroupsofpatientsbeforetreatmentNIHSSscoreandBarthelindexhadnosignificantdifference(P>0.05),theNIHSSscoreofthetwogroupsweredecreasedaftertreatment(P<0.05),butthepatientsintheobservationgroupwasremarkablyhigherthanthatofcontrolgroup(P<0.05group);twopatientswithBarthelindexwereincreasedaftertreatment,buttheobservationgroup(P<0.05)patientswithelevatedlevelwassignificantlyhigherthanthecontrolgroup(P<0.05);thetwogroupsofpatientsbeforetreatment,nosignificantdifferenceinNIHSSscoreofconsciousness,gaze,vision,facialparalysis,upperlimbsandlowerlimbsandlanguagescores(P>0.05),aftertreatment,thescoreofthetwogroupsdecreased(P<0.05),buttheobservationgroupwassignificantlylowerthanthecontrolgroup(P<0.05),withstatisticalsignificance.Twogroupsofpatientsbeforetreatment,TG,TC,LDL-Clevelswerenotsignificantlydifferent(P>0.05),thetwogroupsaftertreatmentinpatientswithTG,TCandLDL-Clevelsweresignificantlydecreased,andtheobservationgroupTG,TCandLDL-Clevelsweresignificantlylowerthanthatofthecontrolgroup(P<0.05);thebloodrheologylevelisnosignificantdifferencebetweentwogroups(P>0.05),twogroupsofpatientswithbloodrheologyindexesweredecreasedaftertreatment,buttheobservationgroupwasremarkablyhigherthanthatofcontrolgroup(P<0.05),withstatisticalsignificance.Conclusion:JiaweiBuyanghuanwuDecoctionCombinedwithwesternmedicineisbeneficialtoimproveneurologicalfunction,improvedailylifeability,reducebloodlipidandimprovehemorheologyinpatientswithcerebralinfarction.
KeyWordsCerebralinfarction;YiqiHuoxue;Buyanghuanwudecoction;Westernmedicine
中图分类号:R255.2文献标识码:Adoi:10.3969/j.issn.1673-7202.2018.06.021
脑梗死又称为缺血性脑卒中,其病理是脑部血液供应障碍,缺血、血氧从而造成局限性脑组织缺血性软化或者坏死。此疾病可在任何年龄段出现,坏死程度也会因血栓的位置以及大小而有所差异,大多数患者均为45~70岁的中老年人。随着我国人口老龄化加剧,脑梗死发生率呈现不断上升的趋势。脑梗死危害巨大,若不及时治疗则会对患者的生命安全产生威胁。西药是临床常用的脑梗死治疗方法,而这种治疗方法并不能得到長期的治疗效果。本次……
