赵洁雅　夏俊　杨会国　郝耿　马文戈　陈世军

摘 要：以新疆某羊场疑似传染性胸膜肺炎的绵羊为研究对象，对羊只病情和症状进行跟踪记录，对死亡羊只进行剖检；无菌采集病料后通过绵羊支原体PCR和细菌培养的方法进行实验室病原诊断。结果显示，死亡羊只肺部发生实变、黏连、胸膜壁粗糙增厚、气管内有大量白色泡沫，具有典型的纤维素性胸膜肺炎的剖检特征；此外绵羊支原体PCR检测结果为阳性，而细菌培养结果阴性，最终确诊该疫情为绵羊支原体引起的传染性胸膜肺炎。本文通过对绵羊支原体肺炎的临床症状、病理变化、实验室诊断等方面的介绍，以期为今后该病的防控工作提供指导和借鉴。

关键词：绵羊；支原体；诊断；防控

中图分类号：S858.26 文献标识码：A DOI 编码：10.3969/j.issn.1006-6500.2018.07.007

Diagnosis and Prevention of Infectious Pleuropneumonia in Sheep

ZHAO Jieya1， XIA Jun2， YANG Huiguo3， HAO Geng3， MA Wen'ge2， CHEN Shijun2

（1. College of Animal Madicine， Xinjiang Agricultural University， Urumqi， Xinjiang 830000，China； 2.Institute of Veterinary Science， Xinjiang Academy of Animal Science， Urumqi， Xinjiang 830000，China； 3.Institute of Animal Science， Xinjiang Academy of Animal Science， Urumqi， Xinjiang 830000，China）

Abstract： The author took the sheep suspected of infectious pleural pneumonia in a sheep farm in Xinjiang as the research object， recorded the condition and symptoms of the sheep， and dissected the dead sheep. The pathogens were diagnosed by PCR and bacterial culture. The results showed that the lungs of the dead sheep were thickened and clung， the pleural wall was coarse and thickened， there were a lot of white foams in the trachea， which had the characteristic of typical cellulose pleural pneumonia. The PCR test of mycoplasma ovis was positive，while the bacterial culture result was negative， finally confirmed that the epidemic situation was the sheep infectious pleuropneumonia caused by Mycoplasma ovis. The paper introduced the clinical symptoms， pathologic changes and laboratory diagnosis of sheep mycoplasma pneumonia in order to provide guidance and reference for the prevention and control of the disease in the future.

Key words： sheep； Mycoplasma ovis； diagnosis； prevention and control

支原體是目前已知能独立生活的缺乏细胞壁的最小原核微生物[1]，绵羊传染性胸膜肺炎是由绵羊肺炎支原体（Mycoplasma ovipneumoniae，MO）引起的绵羊特有的接触性传染病，该病原微生物由MACKEY等[2]于1963年在英格兰首次从绵羊体内分离得到，以后相继在其他国家和地区均有报道[3]。GEORGE等[4]在澳大利亚昆士兰从间质性肺炎的绵羊中分离到了支原体，后被CARMICHAEL描述并正式命名绵羊肺炎支原体。之后在世界多个国家和地区均有该病的报道，我国四川、新疆、甘肃、河北、云南等多个省区都有该病的发生[5]。此病1～3月龄羔羊易感，以高热、咳嗽、肺和胸膜发生浆液性及纤维素性炎症为主要特征[6]，病变多发生于肺组织的心叶、尖叶、隔叶，病程可达数月至数年。……