肺癌并发上腔静脉综合征的临床综合治疗方案及疗效观察
2018-09-21王奎
王奎
[摘要] 目的 观察肺癌并发上腔静脉综合征的临床综合治疗方案及疗效。 方法 随机选取2013年2月~2015年2月我院收治的肺癌并发上腔静脉综合征患者60例,依据治疗方法将患者分为综合治疗组(介入治疗+适形放疗+常规化疗,n=30)和常规化疗组(n=30),对两组患者的临床疗效、不良反应发生情况、6个月、1年、2年、3年生存情况进行统计分析。 结果 综合治疗组患者的总缓解率为86.7%(26/30),显著高于常规化疗组的60.0%(18/30)(P<0.05);综合治疗组患者的6个月、1年、2年、3年生存率分别为96.7%(29/30)、83.3%(25/30)、66.7%(20/30)、53.3%(16/30)均显著高于常规化疗组80.0%(24/30)、63.3%(19/30)、46.7%(14/30)、33.3%(10/30),差异有統计学意义(P<0.05)。 结论 肺癌并发上腔静脉综合征患者采取综合治疗较常规化疗疗效显著。
[关键词] 肺癌并发上腔静脉综合征;介入治疗;适形放疗;常规化疗
[中图分类号] R734.2 [文献标识码] B [文章编号] 1673-9701(2018)15-0111-03
Comprehensive treatment and curative effect of lung cancer complicated with superior vena cava syndrome
WANG Kui
Department of First Internal Medicine,People's Hospital of Tacheng in the Xinjiang Uygur Autonomous Region,Tacheng 834700,China
[Abstract] Objective To observe the comprehensive treatment and efficacy of patients with lung cancer complicated with superior vena cava syndrome. Methods 60 patients with lung cancer complicated with superior vena cava syndrome treated in our hospital from February 2013 to February 2015 were randomly selected and divided into comprehensive treatment group (interventional therapy+conformal radiotherapy+conventional chemotherapy, n=30) and conventional chemotherapy group(n=30) according to treatment method. The clinical efficacy, occurrence of adverse reactions, and survival at 6 months, 1 year, 2 years, and 3 years of the two groups were statistically analyzed. Results The total remission rate of patients in the comprehensive treatment group(86.7%, 26/30) was significantly higher than that of the conventional chemotherapy group(60.0%, 18/30)(P<0.05). The 6 months, 1 year, 2 years, and 3 years survival rate were 96.7%(29/30), 83.3%(25/30), 66.7%(20/30), 53.3%(16/30) respectively of the conventional chemotherapy group were all significantly higher than those of conventional chemotherapy group[80.0%(24/30), 63.3%(19/30), 46.7%(14/30), 33.3%(10/30)], the difference was statistically significant(P<0.05). Conclusion Comprehensive treatment in patients with lung cancer complicated with superior vena cava syndrome is more effective than conventional chemotherapy.
[Key words] Lung cancer complicated by superior vena cava syndrome; Interventional therapy; Conformal radiotherapy; Conventional chemotherapy
肺癌一个最常见的急症,为上腔静脉综合征,其属于一组临床症候群,发生机制为血液回流在上腔静脉不完全性或完全性阻塞的情况下受阻,如没有得到及时有效的治疗,将会对患者的生命安全造成严重威胁。为了对肺癌并发上腔静脉综合征患者进行更好的治疗,从而有效改善患者预后,本研究统计分析了2013年2月~2015年2月我院收治的肺癌并发上腔静脉综合征患者60例的临床资料,比较了肺癌并发上腔静脉综合征患者常规化疗与综合治疗的疗效,现报道如下。
1资料与方法
1.1 一般资料
随机选取2013年2月~2015年2月我院收治的肺癌并发上腔静脉综合征患者60例,纳入标准:所有患者均经X线、CT及病理组织学检查确诊为肺癌并发上腔静脉综合征,预计生存期均在3个月以上;排除标准:将接受过抗肿瘤治疗等患者排除在外[1]。依据治疗方法将这些患者分为综合治疗组(介入治疗+适形放疗+常规化疗,n=30)和常规化疗组(n=30)。……
