谢波

[摘要] 目的 探討茵陈蒿汤治疗黄疸型肝炎的疗效。 方法 选择2010年7月～2017年6月在我院诊断治疗的黄疸型肝炎患者100例为研究对象，随机分为观察组和对照组，各50例。两组均给予核苷类似物口服抗病毒治疗，还原性谷胱甘肽、甘草酸二胺、门冬氨酸钾镁静脉点滴治疗。研究组在此基础上加茵陈篙汤治疗。比较两组治疗前后转氨酶水平与胆红素水平，比较治疗后效果。 结果 两组治疗后转氨酶均较治疗前显著下降，差异有统计学意义（P<0.05）；研究组治疗后转氨酶均较对照组低，差异显著（P<0.05）。治疗后，两组总胆红素、直接胆红素均较治疗前下降，差异显著（P<0.05）；治疗后，研究组总胆红素与直接胆红素均显著低于对照组，差异有统计学意义（P<0.05）。研究组总有效率为98.0%，显著高于对照组的74.0%。差异有统计学意义（P<0.05）。 结论 在常规治疗基础上加用茵陈篙汤治疗黄疸型肝炎能够显著提高临床疗效，改善肝功能，降低胆红素水平。

[关键词] 茵陈蒿汤；肝炎；黄疸；还原性谷胱甘肽；甘草酸胺；门冬氨酸钾镁

[中图分类号] R259 [文献标识码] B [文章编号] 1673-9701（2018）15-0108-03

Clinical effect of Yinchenhao Decoction in the treatment of icteric hepatitis

XIE Bo

Ulanqab Central Hospital of Inner Mongolia，Ulanqab 012000，China

[Abstract] Objective To study the clinical effect of Yinchenhao Decoction in the treatment of icteric hepatitis. Methods 100 cases with icteric hepatitis diagnosed and treated in our hospital from July 2010 to June 2017 were selected as the research subjects and were randomly divided into observation group and control group， with 50 cases in each group. Both the two groups were given oral antiviral treatment with nucleoside analogues and drip therapy of reduced glutathione， diammonium glycyrrhizinate and potassium aspartate magnesium. The observation group added Yinchenhao Decoction in the foundation of the control group. The levels of transaminase and bilirubin before and after treatment in two groups， and the effects after treatment of the two groups were compared. Results The transaminase levels in the two groups after treatment were significantly lower than those before treatment（P<0.05）. The transaminase level in observation group was lower than that in the control group after treatment， and the difference was significant （P<0.05）. The total bilirubin and direct bilirubin in the two groups were significantly lower than those before treatment（P<0.05）， and the total bilirubin and direct bilirubin in the observation group were significantly lower than those in the control group， the differences were statistically significant（P<0.05）. The total effective rate of the observation group was 98%， which was significantly higher than that of the control group at 74%， the difference was statistically significant（P<0.05）. Conclusion Yinchenhao Decoction in the foundation of regular treatment in the treatment of icteric hepatitis can significantly promote the clinical effect， improve liver function and reduce bilirubin level.

[Key words] Yinchenhao Decoction；Hepatitis；Jaundice；Reduced glutathione；Diammonium glycyrrhizinate；Potassium aspartate magnesium

黄疸型肝炎包括甲肝、乙肝、丁肝、戊肝等，巩膜、皮肤出现黄染，主要表现为黄疸。患者从发病数天至2周逐渐开始出现黄疸，患者可伴有发热、畏寒，甚至出现高热。此外，患者还会出现乏力、食欲下降、恶心、呕吐，厌油腻，上腹胀闷，尿黄，大便较稀或便秘。茵陈蒿汤是中药方剂，具有清热、利湿、退黄的功效[1-3]。本研究采用茵陈蒿汤用于黄疸型肝炎的治疗，现报道如下。

1 资料与方法

1.1 一般资料

选择2010年月～2017年6月在我院诊断治疗的黄疸型肝炎患者100例为研究对象。纳入标准：患者为慢性病毒性肝炎，以黄疸为主要症状，中医辨证为“阳黄”，患者对治疗知情同意。排除标准：辨证为湿热黄疸证，其他原因导致的黄疸，不同意参加本次研究。100例患者随机分为观察组和对照组，各50例。两组患者一般资料匹配，无显著差异（P>0.05）。见表1。本研究经过医院医学伦理会同意。