卢军占

【摘 要】 目的：觀察中西医结合治疗对原发性高血压痰湿壅盛型患者疗效、血液流变学、血压控制的影响。方法：选取原发性高血压痰湿壅盛型患者106例，随机分为观察组与对照组各53例。对照组单纯采取常规西医降压治疗，观察组在对照基础上加用半夏白术天麻汤、升降散治疗，均治疗1个月。对比两组治疗效果、不良反应发生率与治疗前、治疗1个月后血压[收缩压（SBP）、舒张压（DBP）]、血液流变学指标（全血高切黏度、全血低切黏度）水平。结果：观察组治疗1个月后总有效率86.79%（46/53）高于对照组69.81%（37/53），差异有统计学意义（P<0.05）；两组治疗前SBP及DBP水平相比，差异无统计学意义（P>0.05），两组治疗1个月后SBP及DBP水平均较治疗前降低，且观察组低于对照组（P<0.05）；两组治疗前全血高切黏度、全血低切黏度对比，差异无统计学意义（P>0.05），两组治疗1个月后全血高切黏度、全血低切黏度均较治疗前降低，且观察组亦低于对照组（P<0.05）；观察组不良反应发生率15.09%（8/53）与对照组11.32%（6/53）比较，差异无统计学意义（P>0.05）。结论：原发性高血压痰湿壅盛型患者予以中西医结合治疗可明显提升临床疗效，控制患者血压水平，改善血液流变学状况，且具有一定安全性，值得临床推广应用。

【关键词】 原发性高血压；痰湿壅盛型；半夏白术天麻汤；升降散；血压控制；血液流变学

【中图分类号】R544.1 【文献标志码】 A 【文章编号】1007-8517（2018）14-0109-04

Abstract：Objective To explore the effect of integrated traditional Chinese and Western Medicine on the efficacy， hemorheology and blood pressure control of patients with primary hypertension in stagnation of phlegm-dampness type. Methods 106 patients with primary hypertension in stagnation of phlegm-dampness type in our hospital were randomly divided into observation group and control group with 53 cases in each group. The control group was treated with conventional western medicine， and the observation group was treated with Banxia Baizhi Tianma Decoction and Shengjiang powder on the basis of the control group，and the treatment were continued for 1 month. The effect of treatment， the incidence of adverse reactions， and the levels of blood pressure [systolic pressure （SBP）， diastolic pressure （DBP）] and hemorheological indexes （whole blood high shear viscosity， whole blood low shear viscosity） before and after 1 months of treatment of two groups were compared. Results The total effective rate of the observation group after treatment for 1 month was 86.79% （46/53）， higher than that of the control group 69.81% （37/53），and the differences between the two goups were statistically significant（P<0.05）. There was insignificant difference in the levels of SBP and DBP between the two groups before treatment（P>0.05）. After two months of treatment， the levels of SBP and DBP in both groups were lower than those before treatment， and the observation group was lower than the control group after treatment for 1 month（P<0.05）. There was insignificant difference in high viscosity of whole blood and low shear viscosity of whole blood between the two groups before treatment（P>0.05）. After two months of treatment， the high viscosity of whole blood and low shear viscosity of whole blood decreased after treatment for 1 month， and the observation group was also lower than the control group（P<0.05）. The incidence of adverse reactions in the observation group was 15.09% （8/53）， and there was insignificant difference compared with 11.32% （6/53） in the control group（P>0.05）. Conclusion The integrated traditional Chinese and Western Medicine in the treatment of patients with primary hypertension in stagnation of phlegm-dampness type can significantly improve the clinical curative effect， improve the level of blood pressure control， and improve the hemorheology condition. Besides， it has certain safety.It is worthy of clinical promotion.

Keywords：Primary Hypertension；Stagnation of Phlegm-dampness Type；Banxia Baizhu Tianma Decoction；Shengjiang Powder；Blood Pressure Control； Hemorheology

原发性高血压属于高血压病最常见类型，中老年人为高发群体，病因与肥胖、饮酒、遗传、精神紧张等密切相关，随疾病进展可对患者腎、心、脑等靶器官造成严重损伤，致使其产生冠心病、脑卒中等疾病的风险显著增加[1]。目前药物治疗为治疗该病的重要方法，主要治疗目标为控制患者血压水平，有效降低其心血管并发症及死亡的发生风险。……