柯琼可

【摘 要】 目的：观察中西医结合治疗喘息性支气管炎的疗效。方法：选取喘息性支气管炎患儿108例为研究对象，随机分为对照组与观察组各54例。对照组给予抗病毒、抗炎、雾化吸入等常规治疗，观察组在对照组基础上加用百咳宁颗粒治疗，治疗1周后比较两组疗效、临床症状好转时间及住院时间、炎性因子指标。结果：对照组总有效率81.5%，明显低于观察组的94.4%（P<0.05）；观察组咳嗽消失时间、气喘消失时间、哮鸣音消失时间均短于对照组组（P<0.05），但两组住院时间比较无统计学差异（P>0.05）；治疗后观察组的ECP、CRP均显著低于对照组（P<0.05）；两组组不良反应发生率无统计学差异（P>0.05）。结论：中西医结合治疗喘息性支气管炎临床疗效明显，且无明显不良反应，值得推广应用。

【关键词】 支气管炎；喘息性；百咳宁颗粒

【中图分类号】R562.2+1 【文献标志码】 A【文章编号】1007-8517（2018）06-0116-03

Abstract：Objective To observe the effect of combination of traditional Chinese and Western medicine in the treatment of asthmatic bronchitis. Methods 108 children with asthmatic bronchitis were selected as the research object， and the random numbers were divided into the control group and the observation group （54 cases each）. The control group was treated with antiviral， anti-inflammatory， atomizing inhalation and other conventional treatment. The observation group was treated with Bai Ke Ning Granule on the basis of the control group. After 1 weeks of treatment， the curative effect， improvement time of clinical symptoms， hospitalization time and inflammatory factors were compared between the two groups. Results The control group was 81.5%， significantly lower than the observation group 94.4% （P<0.05）； observation group， the disappearance time of cough， asthma， wheezing disappearance time disappeared time was shorter than the control group （P<0.05）， but the two groups had no significant difference in hospitalization time （P>0.05）； after treatment， observation group ECP， CRP were significantly lower than the control group （P<0.05）； the two groups the incidence of adverse reactions was no significant difference （P>0.05）. Conclusion The combination of traditional Chinese and Western medicine is effective in the treatment of asthmatic bronchitis with no obvious adverse reactions. It is worth popularizing.

Keywords：Bronchitis； Wheezing； Bai Ke Ning Granules

喘息性支气管炎是婴幼儿较为常见的一种呼吸系统疾病，通常好发于5岁以下儿童，其中以呼吸道合胞病毒感染较为常见，约占致病菌的50%～80%，无典型临床症状，多继发于上呼吸道感染，伴低度、中度发热及刺激性干咳，同时还可出现肺部哮鸣音及粗湿罗音[1]。本病好发于冬春两季，经治疗后上述症状可明显减轻，近期预后良好，但喘息性支气管炎患儿存在支气管痉挛、黏液分泌物增多等非特异性炎症反应，具有自限性，至6岁以后哮鸣多不再发生，但患病期间，患儿因喘息造成活动不便，生长代谢受阻，降低其生活质量[2]。据相关研究表明[3-4]，1岁以下的呼吸道合胞病毒支气管炎患儿，其7年随访期间反复喘息及哮喘的发生率依次为68%、30%，其远期预后不佳，而长期、反复用药可出现耐药性，亦不利于患儿生长发育。……