CO2—DSA在小肠出血诊断中的价值
2018-06-13卢伟杨超张嘉诚杨剑杜鹏马军朋张哲蒋富强
卢伟 杨超 张嘉诚 杨剑 杜鹏 马军朋 张哲 蒋富强
[摘要] 目的 比较CO2-DSA和非离子碘造影剂在诊断小肠出血中的作用。 方法 选择2015年10月~2017年6月在中国人民解放军海军总医院确诊为小肠出血患者20例分别用CO2和碘造影剂行肠系膜上、肠系膜下动脉造影,并超选择到疑似出血部位的肠系膜上、下动脉3级分支重复造影,采用盲法评价两种造影剂显示消化道出血的阳性率。 结果 在肠系膜上、下动脉主干造影时,CO2显示7例(7/20),碘造影劑显示9例(9/20),两组比较差异无统计学意义(χ2=0.417,P > 0.05)。在超选择到肠系膜动脉3级分支造影时,CO2-DSA显示20例消化道出血中的19例(95.0%),碘造影剂-DSA显示14例(70.0%),差异有统计学意义(χ2=4.329,P < 0.05)。 结论 在超选择到接近出血靶动脉造影时,CO2气体在显示小肠出血比常规碘造影剂更具优势。
[关键词] 消化道出血;血管造影;二氧化碳;碘造影剂
[中图分类号] R445.3 [文献标识码] A [文章编号] 1673-7210(2018)04(a)-0118-04
[Abstract] Objective To compare the role of CO2-DSA and non-ionic iodine contrast agent in diagnosis of intestinal bleeding. Methods 20 cases of patients with small intestinal bleeding treated in Navy General Hospital of People′s Liberation Army from October 2015 to June 2017 were selected. Superior and inferior mesenteric arteries angiography were performed in 20 patients by use of both CO2 and iodinated contrast agent. Repeated angiography was performed with super-selective catheterization of the third level branches of suspected arteries. The images were evaluated blindly. The positive depicted of bleeding in both CO2 and iodine contrast agents were compared. Results Small intestinal bleeding was demonstrated in 7 cases (7/20) with CO2-DSA, while 9 cases with iodine contrast agent-DSA (9/20), there was no significant difference between the two groups (χ2=0.417, P > 0.05). Small intestinal bleeding was showed in 19 of the 20 cases by CO2-DSA (95.0%), while 14 cases (70.0%) by iodine contrast agents, with statistically significant difference (χ2=4.329, P < 0.05). Conclusion CO2 gas is superior to iodine contrast agent in demonstrating small intestinal bleeding in case of super-selective catheterization near the bleeding arteries.
[Key words] Gastrointestinal bleeding; Angiography; Carbon dioxide; Iodine contrast agent
消化道出血是临床上常见的疾病,通过内镜检查,大多能确定出血部位和原因,但仍有其局限性,如大量出血时,难以显示具体出血的部位,另外,空、回肠是内镜检查的盲区。虽然核素扫描对肠道出血检出率较高,但是,但其定位、定性能力差,有30%的假阳性和40%的定位错误。动脉血管造影对诊断出血的部位和原因有较大帮助,目前已成为明确消化道出血部位和病因诊断的主要方法之一。动脉造影明确出血部位后,行出血动脉栓塞是控制出血的重要手段之一,但其阳性率一般只有50%~60%,尤其血流量<0.5 mL/min时,血管造影常常难以明确出血位置[1-2]。有研究表明,应用CO2气体行动脉造影能提高消化道出血的检出率[2-3]。由于CO2气体的可被压缩性和CO2为阴性造影剂等特点,需要特殊的注射器和采集成像参数,使得该项技术该项一直以来在临床上应用较少。本……
