张拥军 林奋强 卫玉光

[摘要]目的 探討腰痹通联合甲钴胺治疗腰椎间盘突出症的效果。方法 选取2015年1月～2016年12月在我院接受治疗的腰椎间盘突出症患者94例作为研究对象，按照随机数字法将其分为观察组、对照组，每组47例。对照组患者单用甲钴胺进行治疗，观察组患者采用腰痹通胶囊联合甲钴胺进行治疗。观察记录两组患者的总有效率、治疗前后的视觉模拟评分法（VAS）评分、治疗前后的血清丙二醛（MDA）和超氧化物歧化酶（SOD）水平。结果 观察组治疗4周后的总有效率高于对照组，差异有统计学意义（P<0.05）；治疗后，观察组的VAS评分低于对照组，差异有统计学意义（P<0.05）。治疗后，观察组的血清MDA水平低于对照组，血清SOD水平高于对照组，差异有统计学意义（P<0.05）。结论 腰痹通联合甲钴胺治疗腰椎间盘突出症的效果显著，可有效提升患者的治疗总有效率，在减轻患者疼痛、降低血清MDA水平和提升血清SOD水平方面均具有积极意义，值得临床推广应用。

[关键词]腰痹通；甲钴胺；腰椎间盘突出症；治疗效果

[中图分类号] R681.5+3 [文献标识码] A [文章编号] 1674-4721（2018）2（b）-0151-03

Effect evaluation of Yaobitong combined with Mecobalamin in the treatment of lumbar disc herniation

ZHANG Yong-jun1 LIN fen-qiang1 WEI Yu-guang2

1.Department of Emergency， Changan Hospital of Dongguan City，Guangdong Province，Dongguan 523305，China；2.Department of Pharmacy，Changan Hospital of Dongguan City，Guangdong Province，Dongguan 523305，China

[Abstract]Objective To evaluate the effect of Yaobitong combined with Mecobalamin in the treatment of lumbar disc herniation.Methods 94 patients with lumbar disc herniation treated in our hospital from January 2015 to December 2016 were selected as the object of this study.They were divided into the observation group （n=47） and control group （n=47） according to the random number method.The patients in the control group were treated with Mecobalamin.The patients in the observation group were treated with Yaobitong Capsules and Mecobalamin.The total effective rate，VAS score before and after treatment，serum MDA and SOD level before and after treatment were observed and recorded in the two groups.Results The total effective rate of observation group after 4 weeks was higher than the control group，and the difference was statistically significant （P<0.05）.After treatment，VAS score of the observation group was lower than the control group，and the difference was statistically significant （P<0.05）.After treatment，serum MDA level in the observed group was lower than that of the control group，and serum SOD level was higher than that of the control group，and the difference was statistically significant （P<0.05）.Conclusion The effect of Yaobitong combined with Mecobalamin treating lumbar disc herniation is significant.It can effectively improve the total effective rate of treatment，in reducing the patients′ pain，reducing serum MDA level and enhancing the serum SOD level shows a positive significance.It is worthy of clinical promotion and application.

[Key words]Yaobitong；Mecobalamin；Lumbar disc herniation；Treatment effect

腰椎间盘突出症是一种临床常见的骨科疾病，是由于椎间盘变形和纤维环破裂导致相邻脊神经根遭受刺激或压迫表现出的综合征[1]，中年人为高发人群，但现已呈现年轻化趋势[2]。目前临床上对椎间盘突出症的治疗，主要有手术和非手术两种方法[3]，与手术治疗方法比较，非手术治疗方法对患者造成的损伤更少[4]，因而，对于椎间盘突出症的治疗可优先考虑非手术治疗法[5]。有研究报道，采用中西结合的治疗方法，在保证效果的同时还可提升治疗安全性[6]。本研究通过观察患者的临床表现，探讨腰痹通联合甲钴胺治疗腰椎间盘突出症的效果，现报道如下。

1资料与方法

1.1一般资料

选取2015年1月～2016年12月在我院接受治疗的腰椎间盘突出症患者94例作为研究对象，本次研究通过医院伦理委员会的批准，经患者及其家属同意并签署书面同意书。……