联用美托洛尔和胺碘酮治疗冠心病室性心律失常的效果评价
2018-01-21叶芸田龙海
叶芸 田龙海
【摘要】目的 探讨分析冠心病室性心律失常患者,包括室性早搏、室性心动过速等,使用美托洛尔联合胺碘酮治疗的临床效果。方法 选择我院所接收的患冠心病室性心律失常者94例,按治疗时间分组,对照组单纯使用美托洛尔治疗,研究组则给予胺碘酮联合美托洛尔法进行治疗,对比两种方法在患者疗效、血压、心率及心律失常改善方面的临床效果。结果 治疗后研究组的收缩压、舒张压水平、心率及室性早搏、室性心动过速发作次数均低于对照组,差异有统计学意义(P<0.05);对比两组的疗效,研究组的治疗总有效率更高于对照组;差异有统计学意义(P<0.05)。结论 用胺碘酮联合美托洛尔方法进行冠心病室性心律失常治疗,可改善心率与血压水平,提高室颤阈值,具有良好的治疗效果提升作用。
【关键词】美托洛尔;胺碘酮;冠心病;心律失常
【中图分类号】R541 【文献标识码】A 【文章编号】ISSN.2095.6681.2018.32..02
【Abstract】Objective To investigate and analyze the clinical effect of metoprolol combined with amiodarone on ventricular arrhythmia in patients with coronary heart disease, including ventricular premature beats and ventricular tachycardia.Methods 94 patients with ventricular arrhythmia were divided into two groups according to the treatment time. The control group was treated with metoprolol only,while the study group was treated with amiodarone combined with metoprolol.Results After treatment,systolic blood pressure, diastolic blood pressure,heart rate,ventricular premature beats and ventricular tachycardia attacks in the study group were lower than those in the control group (P<0.05), and the total effective rate was higher in the study group than that in the control group (P<0.05).Conclusion Amiodarone combined with metoprolol in the treatment of ventricular arrhythmias in coronary heart disease can improve the heart rate and blood pressure levels, increase the threshold of ventricular fibrillation, and has a good therapeutic effect.
【Key words】Mei TORO M; amiodarone;Coronary heart disease;Arrhythmia
冠心病属于十分常见的心血管疾病类型,而室性心律失常则是该疾病较为严重的病症之一,患有冠心病快速心律失常,尤其是室性心动过速、心室颤动者会提高其心肌耗氧量,易增加心肌缺血的发生几率,从而使其梗死的面积得以不断的扩张,严重时可引起心衰或心衰加重、猝死,威胁到患者的生命安全[1]。临床上多使用药物治疗以及手术对冠心病心律失常患者加以治疗,如射频消融术、埋藏式心脏复律除颤器植入等,单一的药物应用在总的应用效果上并不算理想,因此本研究选我院的冠心病室性心律失常者,用胺碘酮联合美托洛尔药物加以医治,探究此种药物联合治疗法的治疗价值。现报告如下。
1 资料与方法
1.1 一般资料
选取我院2017年7月~2018年6月接收治疗的94例患冠心病室性心律失常者选出,作为此次研究对象,以接受治疗时间顺序为准,共将其分了研究组46例,对照组48例。……
