刘芳 刘元元 杨飞

[摘要] 目的 研究坦白酮症酸中毒患者接受普通胰岛素与诺和锐治疗的效果，给临床治疗提供参考。 方法 2016年1—8月对该院的糖尿病酮症酸中毒患者80例进行了分析研究，将患者分成了对照组和观察组，均有40例，对照组患者接受普通胰岛素治疗，观察组患者接受诺和锐治疗，对两组治疗一段时间的情况进行观察组分析。 结果 治疗一段时间，诺和锐治疗的患者后期胰岛素使用了量平均是（88.6±11.2）U，普通胰岛素治疗的患者平均胰岛素使用量是（432.5±15.3）U，患者体内的症状缓解较快，胰岛素水平和尿酮水平经过治疗能够快速恢复，24 h的血糖变化情况显示，观察组患者的血糖水平比较稳定，低血糖发生次数差异有统计学意义（P<0.05）。 结论 糖尿病酮症酸中毒患者接受诺和锐治疗的效果比较好，能够让患者的病情得到缓解，临床中可以进行推广使用。

[关键词] 普通胰岛素;诺和锐;糖尿病酮症酸中毒

[中图分类号] R587.2          [文献标识码] A          [文章编号] 1672-4062（2018）09（a）-0189-02

Therapeutic Effect of Common Insulin and Nuoherui on the Treatment of Diabetic Ketoacidosis

LIU Fang1， LIU Yuan-yuan2， YANG Fei1

1.Department of Geriatrics， Daqing Oilfield General Hospital， Daqing， Heilongjiang Province， 163000 China; 2.Department of Ultrasound， Daqing People's Hospital， Daqing， Heilongjiang Province， 163316 China

[Abstract] Objective To study the effect of treatment of common insulin and Nuoherui in patients with frankosteric acidosis， and to provide reference for clinical treatment. Methods From January to August 2016， 80 patients with diabetic ketoacidosis in the hospital were analyzed. The patients were divided into the control group and the observation group. With 40 patients in each group. The patients in the control group received general insulin therapy. The patients in the observation group received Nuoherui treatment， and observe analyze the treatment of the two groups for a period of time. Results After treatment for a period of time， the average insulin intake in patients treated with Nuoherui was （88.6±11.2）U， and the average insulin use in patients treated with ordinary insulin was （432.5±15.3）U. The symptoms in patients were relieved faster. Insulin level and urinary ketone level can be quickly recovered after treatment. The 24-hour blood glucose changes showed that the blood glucose level of the observation group was stable and the number of hypoglycemia was statistically different （P<0.05）. Conclusion Patients with diabetic ketoacidosis receive the effect of Nuoherui treatment， which can relieve the patient's condition and can be promoted and used in clinical practice.

[Key words] Ordinary insulin; Nuoherui; Diabetic ketoacidosis

糖尿病是目前中老年群體的高发慢性疾病，该疾病治疗难度大，需要对饮食和生活状态进行调控，糖尿病患者最大的危害就是其并发症。糖尿病酮症酸中毒是糖尿病比较多见的一种并发症，患者发生后，普通的治疗方式不是十分理想，诺和锐是胰岛素类似物，注射给药能够发挥胰岛素的功能，反应快速，效果较好，诺和锐治疗后，患者体内的血糖控制比较理想，可以预防血糖上升，防止血糖过低，对糖尿病酮症酸中毒的治疗有很重要的意义。糖尿病是体内的胰岛素功能失常，胰岛素分泌不足，胰岛素结合受体敏感性降低等引起的体内血糖代谢失常，导致了体内的系统紊乱，血糖上升，有尿糖症状。……