胡燕娟 卢丽金 杨志远 易仕青

[摘要] 目的 探究在高血压合并糖尿病患者心律失常中卡维地洛的临床治疗效果与安全性。方法 将2016年2月—2018年4月收治的86例高血压合并糖尿病患者，随机分组法分成两组，即对照组和观察组，每组43例。对照组给予常规治疗方法，观察组给予卡维地洛治疗方法。结果 血糖、血压及心率指标比较观察组较对照组低，不良反应发生率比较观察组较对照组低，临床治疗效果比较观察组较对照组高，差异有统计学意义（P<0.05）。结论 在高血压合并糖尿病患者心律失常疾病治疗中应用卡维地洛治疗方法，有助于稳定患者的血糖、血压及心率指标、不良反应发生概率明显下降，疾病临床治疗效果明显提升。

[关键词] 卡维地洛;高血压;糖尿病;心律失常

[中图分类号] R59          [文献标识码] A          [文章编号] 1672-4062（2018）09（a）-0006-03

Randomized Controlled Trial of Carvedilol in the Treatment of Arrhythmia in Patients with Hypertension Complicated with Diabetes Mellitus

HU Yan-juan， LU Li-jin， YANG Zhi-yuan， YI Shi-qing

Department of Pharmacy， Clinical Laboratory of Fuzhou General Hospital， Putian， Fujian Province， 351100 China

[Abstract] Objective To investigate the clinical efficacy and safety of carvedilol in patients with hypertension and diabetes mellitus. Methods 86 patients with hypertension and diabetes mellitus from February 2016 to April 2018， were randomly divided into two groups， the control group and the observation group， with 43 cases in each group. The control group was given a conventional treatment method， and the observation group was given a carvedilol treatment method. Results The blood glucose， blood pressure and heart rate indicators were lower in the observation group than in the control group. The incidence of adverse reactions was lower in the observation group than in the control group. The clinical treatment effect was higher in the observation group than in the control group ，the difference was statistically singnificant （P<0.05）. Conclusion The application of carvedilol in the treatment of arrhythmia with hypertension and diabetes is helpful to stabilize the blood glucose， blood pressure and heart rate indicators， the incidence of adverse reactions is significantly reduced， and the clinical treatment effect of the disease is significantly improved.

[Key words] Carvedilol; Hypertension; Diabetes; Arrhythmia

高血壓合并糖尿病属于临床上的一种同源性疾病，两种疾病均有较高的发病概率，属于一种慢性疾病，治疗周期较长，两种疾病共存，会引发患者出现诸多的并发症，患者病死率较高。高血压合并糖尿病疾病的出现，会引发患者出现严重的肾动脉、脑动脉、肠系膜动脉及冠状动脉供血不足情况，患者病死率大大提升，对患者的生命安全造成了极大的威胁。卡维地洛作为临床上高血压合并糖尿病的一种有效治疗药物，属于一种α、β受体阻断剂，对缓解患者的心肌缺血、舒张患者的血管作用显著，已经成为现阶段临床上高血压合并糖尿病的一种有效治疗药物，临床治疗效果显著。该文将该院2016年2月—2018年4月收治的86例高血压合并糖尿病患者作为研究对象，探究在高血压合并糖尿病患者心律失常中卡维地洛的临床治疗效果与安全性，现报道如下。……