新生儿Rh溶血病的临床诊断及治疗
2017-11-27郇庆东
郇庆东
【摘要】 目的 探究新生儿Rh溶血病的临床诊断及治疗。方法 200例Rh血型不合孕产妇作为研究对象, 根据诊断方法不同分为对照组和研究组, 每组100例。对照组运用血型血清学检测方法进行诊断;研究组运用人性化方法进行诊断。两组均根据诊断采取药物治疗。观察两组治疗效果。结果 研究组治疗总有效率为93.0%, 对照组为74.0%, 两组比较差异有统计学意义(P<0.05)。结论 强化临床新生儿Rh溶血病诊断方法, 运用人性化诊断方法对临床Rh血型不合孕产妇进行诊断, 有助于提升临床新生儿Rh溶血病诊断准确率, 为临床疾病治疗提供可靠依据, 提升临床疾病治疗有效性, 可在实际中推广应用。
【关键词】 Rh溶血病;新生儿;诊断;治疗
DOI:10.14163/j.cnki.11-5547/r.2017.31.015
【Abstract】 Objective To investigate the clinical diagnosis and treatment of neonatal Rh hemolytic disease. Methods A total of 200 Rh incompatible maternal women as study subjects were divided by different diagnostic methods into control group and research group, with 100 cases in each group. The control group was diagnosed with blood type serum detection method, and the research group was diagnosed with humanization method. Both groups were treated according to the diagnosis, and their treatment effect was observed. Results The research group had total treatment effective rate as 93.0%, which was 74.0% in the control group, and the difference was statistically significant (P<0.05). Conclusion Strengthening the clinical diagnosis of neonatal Rh hemolytic disease, along with humanized diagnosis method for diagnosis of maternal women with clinical Rh incompatibility, helps to improve the diagnostic accuracy of neonatal Rh hemolytic disease, provide reliable basis for clinical treatment of the disease, and improve clinical efficacy. It can be promoted and applied in practice.
【Key words】 Rh hemolytic disease; Newborn; Diagnosis; Treatment
本研究對本院收治的200例Rh血型不合的孕产妇作为研究对象, 对其资料进行统计分析, 研究临床新生儿Rh溶血病的诊断及治疗。现报告如下。
1 资料与方法
1. 1 一般资料 选择2014年3月~2015年9月在本院进行检测的200例Rh血型不合孕产妇作为本次对象, 符合临床Rh血型不合诊断标准[1], 根据诊断方法不同将其分为研究组和对照组, 每组100例。研究组孕产妇年龄23~38岁, 平均年龄(20.5±5.8)岁, 孕周27~36周, 平均孕周(30.1±2.0) 周, 初次孕产妇50例, 再次孕产妇50例;对照组孕产妇年龄23~38岁, 平均年龄(20.5±5.8)岁, 孕周27~36周, 平均孕周(30.1±2.0) 周, 初次孕产妇50例, 再次孕产妇50例。两组孕产妇一般资料比较差异无统计学意义(P>0.05), 具有可比性。
1. 2 方法
1. 2. 1 对照组在临床诊断疾病中, 对Rh血型不合的孕产妇运用血型血清学检测方法。凝聚胺polybrene试剂盒(珠江的贝索生物技术有限公司)、抗人球蛋白试剂(上海的血液生物医药有限责任公司)、Rh血型分型试剂(上海的血液生物医药有限责任公司)、血液免疫学专用离心机KA-2200(日本久保田公司)作为工具, 进行检测。Rh血型鉴定中, 患儿血清和释放液与母亲血清通过筛选细胞、谱细胞凝聚胺法检测Rh系统抗体特异性, 并进行O型红细胞吸收、放散实验, 鉴定诊断疾病。对……
