阿奇霉素序贯疗法治疗小儿支原体肺炎的分析
2017-09-25王亚莲
王亚莲


[摘要] 目的 分析研究阿奇霉素序贯疗法治疗小儿支原体肺炎的临床效果。方法 随机选择2013年12月—2014年12月间在该院医治的100例小儿支原体肺炎患者作为研究对象,按照患者的意愿随机将其分成治疗组和对照组,每组50例;治疗组予以阿奇霉素序贯疗法,对照组予以红霉素进行治疗;将两组患者的治疗效果、不良反应发生率、症状消失时间、住院时间进行对比分析。结果 治疗组患者的治疗总有效率(96.00%)、不良反应率(10.00%)、发热消失时间(3.8±1.5)d、咳嗽消失时间(3.3±0.4)d、肺罗音消失时间(5.6±2.2)d、住院时间(8.4±1.6)d均显著优于对照组患者治疗总有效率(82.00%)、不良反应率(22.00%)、发热消失时间(4.7±1.6)d、咳嗽消失时间(4.6±0.3)d、肺罗音消失时间(7.8±2.5)d、住院时间(11.2±2.3)d,组间比较差异有统计学意义(P<0.05)。结论 在小儿支原体肺炎的治疗中采用阿奇霉素序贯疗法,具有治疗有效率高、症状消失时间短、不良反应低、住院时间短等优势,具有较高的治疗价值,值得临床借鉴。
[关键词] 阿奇霉素序贯疗法;小儿支原体肺炎;治疗效果
[中图分类号] R725 [文献标识码] A [文章编号] 1674-0742(2017)07(a)-0120-03
Analysis of Zaithromycin Sequential Therapy for Children with Mycoplasma Pneumonia
WANG Ya-lian
Department of Pediatrics, Jianshui Peoples Hospital, Jianshui, Yunnan Province, 654399 China
[Abstract] Objective To analyze and research the clinical effect of zaithromycin sequential therapy for children with mycoplasma pneumonia. Methods 100 cases of children with mycoplasma pneumonia admitted and treated in our hospital from December 2013 to December 2014 were selected and randomly divided into two groups with 50 cases in each, the treatment group and the control group respectively adopted the zaithromycin sequential therapy and erythrocin, and the treatment effect, incidence rate of adverse reactions, symptom disappearance time and length of stay were compared and analyzed. Results The total treatment effective rate, adverse reaction rate, fever disappearance time, cough disappearance time, lung rale disappearance time and length of stay in the treatment group were obviously better than those in the control group, [96.00%, 10.00%, (3.8±1.5)d, (3.3±0.4)d, (5.6±2.2)d, (8.4±1.6)d vs 82.00%, 22.00%, (4.7±1.6)d, (4.6±0.3)d, (7.8±2.5)d, (11.2±2.3)d], and all differences were statistically significant(P<0.05). Conclusion The zaithromycin sequential therapy for children with mycoplasma pneumonia has the advantages of high treatment effective rate, short symptom disappearance time, low adverse reactions and short length of stay and higher treatment value, and it is worth clinical reference.
[Key words] Zaithromycin sequential therapy; Children with mycoplasma pneumonia; Treatment effect
小兒支原体肺炎是临床上一种较为常见的小儿呼吸道疾病,其是由支原体感染所造成的、呈间质性肺炎及毛细支气管炎样改变[1]。主要症状为:发热、咳嗽、头痛、咽痛等呼吸道症状[2],该病一年四季均可发病,潜伏期通常为2~3周,传播的途径主要是患儿的口、鼻分泌物经空气飞沫传播[3]。若患儿没有得到及时的治疗,往往能引发多种并发症。临床治疗经常使用阿奇霉素、克拉霉素、红霉素、罗红霉素等予以治疗[4]。近几年来,临床采用阿奇霉素序贯疗法治疗小儿肺炎的疗效显著,为此,该文把2013年12月—2014年12月间在该院医治的100例小儿支原体肺炎作为观察对象,其中50例患儿采用阿奇霉素序贯疗法进行治疗,现报道如下。……
